Brandes W, Santiago T, Limacher M
Department of Medicine, University of Florida College of Medicine, Gainesville.
Clin Cardiol. 1990 Oct;13(10):741-4. doi: 10.1002/clc.4960131015.
A 36-year-old man presented with a prolonged history of chest pain, and was given two sublingual nitroglycerin tablets. Subsequently, the patient became hypotensive, bradycardiac, apneic, and lost consciousness. The bradycardia resolved spontaneously. No evidence for acute myocardial infarction or ischemic disease was found. Thirty-four cases reported to date are reviewed, demonstrating that this response appears to be an independent effect of nitroglycerin taken in any form, in patients with and without myocardial infarction and to be unpredictable, especially without evidence of inferior or right ventricular infarction. Careful monitoring is warranted when administering nitroglycerin.
一名36岁男性因胸痛病史较长前来就诊，服用了两片舌下硝酸甘油片。随后，患者出现低血压、心动过缓、呼吸暂停并失去意识。心动过缓自行缓解。未发现急性心肌梗死或缺血性疾病的证据。对迄今报道的34例病例进行了回顾，结果表明，这种反应似乎是硝酸甘油以任何形式服用后的一种独立效应，无论患者有无心肌梗死，且这种反应不可预测，尤其是在没有下壁或右心室梗死证据的情况下。使用硝酸甘油时需仔细监测。
