Department of Medicine I, NOZ, Erlangen, Germany.
Ultraschall Med. 2011 Apr;32(2):148-53. doi: 10.1055/s-0029-1245934. Epub 2011 Jan 11.
The goal of this study was to assess the informative value of contrast-enhanced ultrasound after radiofrequency ablation (RFA). Patients who had undergone RFA of malignant liver tumors were followed up with contrast-enhanced sonography (CEUS), computed tomography (CT) and/or magnetic resonance tomography (MRI), and the outcomes were compared.
76 patients undergoing 194 RFAs for 118 hepatic neoplasms (n = 55 HCC, n = 63 metastases) in the course of a 7-year period were examined post-interventionally using CEUS and CT or MRI. During follow-up (gold standard of evaluation), contrast agent rim accumulations with a diameter greater than 5 mm and a growth rate of at least 25 % were counted as a recurrence.
CEUS-CT comparison group: A total of 65 scan pairs were compared. In 54 cases (83.1 %) the findings were the same with either method. In 7 cases (10.8 %) CEUS confirmed the correct diagnosis, and in 2 cases (3.1 %) only CT was correct. In 2 cases (3.1 %) both methods yielded incorrect results. Diagnostic accuracy (DA): CEUS 93.8 %, CT 86.2 %. CEUS-MRI comparison group: In 23 cases (88.5 %) of a total of 26 scan pairs, the findings were the same for both CEUS and MRI. In 3 discordant cases only CEUS confirmed the correct diagnosis (3 cases, 11.5 %). Diagnostic accuracy DA (n = 26): CEUS 100 %, MRI 88.4 %.
CEUS performs equally to CT and MRI in the follow-up of patients treated for liver tumors by RFA.
本研究旨在评估射频消融（RFA）后超声造影（CEUS）的信息价值。对接受 RFA 治疗的恶性肝肿瘤患者进行 CEUS、计算机断层扫描（CT）和/或磁共振成像（MRI）随访，并对结果进行比较。
7 年间对 76 例 118 个肝脏肿瘤患者（55 例 HCC，63 例转移瘤）行 194 次 RFA，术后均行 CEUS 及 CT 或 MRI 检查。在随访期间（评估的金标准），以直径大于 5mm 且生长速度至少 25%为标准，计算对比剂边缘积聚的复发例数。
CEUS-CT 比较组：共比较了 65 对扫描结果。两种方法的结果相同者 54 例（83.1%），CEUS 证实正确诊断 7 例（10.8%），CT 正确 2 例（3.1%），两种方法均不正确 2 例（3.1%）。诊断准确性（DA）：CEUS 93.8%，CT 86.2%。CEUS-MRI 比较组：共 26 对扫描中，23 对（88.5%）结果相同，3 对（11.5%）仅 CEUS 结果正确。DA（n=26）：CEUS 100%，MRI 88.4%。
CEUS 在 RFA 治疗肝肿瘤患者的随访中与 CT 和 MRI 同样有效。
