[Changes in 3H-noradrenaline activity in the adrenals and serum of rats under the influence of histamine and adrenocorticotropic hormone].

The authors examined the changes in the distribution of 3H-noradrenaline in the adrenal glands and serum of white rats-control and experimental-after administration of histamine and ACTH. The results from the experiments revealed characteristic curves of accumulation of 3H-noradrenaline in the adrenal glands of the examined animals, with maximum at the tenth minute and characteristic changes in the activity of the labeled noradrenaline in the adrenals and serum after administration of histamine and ACTH, followed up to the second hour. On the basis of the obtained results from the radiometric examination and from the follow-up of the level of the blood sugar, the authors make inferences for the sequence and character of the processes of incorporation and release of catecholamine from the adrenal glands under the action of ACTH and histamine.