Blanc J J, Salaun J P, Mansourati J, Genet L, Etienne Y, Penther P, Boschat J, Gilard M
Service de cardiologie Himbert, Centre hospitalier régional de Brest, France.
Arch Mal Coeur Vaiss. 1990 Sep;83(10):1539-44.
Myocardial ischemia usually presents with chest pain, the characteristics of which are well known. However, anginal pain may be absent during true ischemia, an entity known as painless or silent myocardial ischemia. Does this type of ischemia have special clinical, angiographic or ergometric characteristics after posterior myocardial infarction (MI)? In order to answer this question 183 consecutive patients with recent posterior MI who had undergone coronary angiography and who had positive exercise stress tests on bicycle ergometers were separated into two groups depending on whether they had experienced at least one episode of pain after the acute phase of myocardial infarction or during the exercise stress test (Group S: 83 patients, average age 54 +/- 10 years) or not (Group A: 100 patients, average 54 +/- 8 years). The following parameters were commoner in Group A: cigarette smoking, heart rate and load developed during exercise stress testing provoking electrical signs of ischemia, single vessel disease on coronary angiography, long-term medical treatment. On the other hand, the following parameters were statistically more frequent in Group S: hypercholesterolemia, preinfarction angina, degree of ST depression during exercise testing, reperfusion of the distal vessels of the occluded artery responsible for the infarct by a collateral circulation, triple vessel disease and surgical treatment. However long-term follow-up (average 3 years) shows that mortality and recurrence of MI are similar in both groups.(ABSTRACT TRUNCATED AT 250 WORDS)
心肌缺血通常表现为胸痛,其特征众所周知。然而,在真正的缺血期间可能没有心绞痛,这种情况称为无痛或无症状心肌缺血。在后壁心肌梗死(MI)后,这种类型的缺血是否具有特殊的临床、血管造影或运动测试特征?为了回答这个问题,将183例近期后壁MI且已接受冠状动脉造影且自行车运动测试结果呈阳性的连续患者,根据他们在心肌梗死急性期后或运动测试期间是否经历过至少一次疼痛发作分为两组(S组:83例患者,平均年龄54±10岁)或未经历过疼痛发作的组(A组:100例患者,平均年龄54±8岁)。以下参数在A组中更为常见:吸烟、运动测试期间诱发缺血电信号时的心率和负荷、冠状动脉造影显示单支血管病变、长期药物治疗。另一方面,以下参数在S组中在统计学上更为常见:高胆固醇血症、梗死前心绞痛、运动测试期间ST段压低程度、梗死相关闭塞动脉远端血管通过侧支循环再灌注、三支血管病变和手术治疗。然而,长期随访(平均3年)显示两组的死亡率和心肌梗死复发率相似。(摘要截短至250字)