Juillière Y, Danchin N, Grentzinger A, Suty-Selton C, Perrin O, Guenoun P, Pernot C, Cherrier F
Département de cardiologie, CHU Nancy-Brabois, Vandoeuvre-lès-Nancy.
Arch Mal Coeur Vaiss. 1990 Oct;83(11):1679-84.
The aim of this retrospective study was to determine the relationship between the duration of preceding angina pectoris, collateral circulation and left ventricular function after isolated coronary occlusion with or without myocardial infarction. Coronary angiography of 138 consecutive patients showed isolated and complete occlusions of the left anterior descending (58 patients) or right coronary artery (80 patients). One hundred and four patients had myocardial infarction with (Group A, n = 21) or without (Group B, n = 83) preceding angina pectoris and 34 had angina without myocardial infarction (Group C). The left ventricular ejection fraction was measured by ventriculography in the 30 degrees right anterior oblique projection. The collateral circulation was assessed by coronary angiography and evaluated as follows: no flow or flow limited to collateral branches (subgroup 1) and partial or complete filling of the epicardial arterial segment (subgroup 2). In the global population the left ventricular ejection fraction was higher and the duration of preceding angina pectoris was longer in the subgroups with a well developed collateral circulation. There was no difference in ejection fraction between Groups A and B (presence of myocardial infarction), on the other hand, within each of the groups, a good collateral circulation (subgroup 2) was associated with a significantly higher ejection fraction. Group C (without infarction) patients had better ejection fractions than Groups A or B, especially when the collateral circulation was poorly developed. Within Group C, the quality of the collateral circulation did not seem to affect the ejection fraction. The left ventricular ejection fraction is lower in patients with isolated coronary occlusion and myocardial infarction.(ABSTRACT TRUNCATED AT 250 WORDS)
这项回顾性研究的目的是确定在孤立性冠状动脉闭塞伴或不伴心肌梗死的情况下,既往心绞痛持续时间、侧支循环与左心室功能之间的关系。对138例连续患者进行冠状动脉造影,结果显示左前降支(58例患者)或右冠状动脉(80例患者)存在孤立性完全闭塞。104例患者发生心肌梗死,其中有(A组,n = 21)或无(B组,n = 83)既往心绞痛,34例有不伴心肌梗死的心绞痛(C组)。通过心室造影在右前斜30度投影下测量左心室射血分数。通过冠状动脉造影评估侧支循环,并按以下方式进行评价:无血流或血流仅限于侧支分支(亚组1)以及心外膜动脉段部分或完全充盈(亚组2)。在总体人群中,侧支循环良好的亚组左心室射血分数较高,既往心绞痛持续时间较长。A组和B组(存在心肌梗死)之间的射血分数无差异,另一方面,在每组中,良好的侧支循环(亚组2)与显著较高的射血分数相关。C组(无梗死)患者的射血分数优于A组或B组,尤其是在侧支循环发育不良时。在C组内,侧支循环的质量似乎不影响射血分数。孤立性冠状动脉闭塞并心肌梗死患者的左心室射血分数较低。(摘要截短于250字)