传染性软疣病毒引起的皮肤病变中的抗病毒反应差异。

Disparate antiviral responses in Molluscum contagiosum virus-induced skin lesions.

机构信息

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA.

出版信息

J Invest Dermatol. 2011 Feb;131(2):288-90. doi: 10.1038/jid.2010.368.

DOI:10.1038/jid.2010.368

Abstract

Molluscum contagiosum virus (MCV) is a poxvirus that causes tumor-like skin lesions. New evidence indicates that plasmacytoid dendritic cells, type I interferon production, and interferon-induced dendritic cells have prominent roles in anti-MCV responses, and these features characterize the inflammatory response in lesions that will likely undergo spontaneous regression.

摘要

传染性软疣病毒（MCV）是一种引起肿瘤样皮肤损伤的痘病毒。新证据表明，浆细胞样树突状细胞、I 型干扰素产生和干扰素诱导的树突状细胞在抗 MCV 反应中发挥重要作用，这些特征是病变中发生自发消退的炎症反应的特点。