Genome-wide association studies and cancer.
作者信息
Jorgenson Eric, Cheng Iona
机构信息
Department of Neurology, Ernest Gallo Clinic and Research Center at the University of California, San Francisco, Emeryville, CA 94608, USA.
出版信息
Hawaii Med J. 2010 Oct;69(10):249-51.
Abstract
摘要
相似文献
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Genome-wide association studies and cancer.全基因组关联研究与癌症
Hawaii Med J. 2010 Oct;69(10):249-51.
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Genome-wide association studies and "the art of the soluble".全基因组关联研究与“可溶性的艺术”
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Are we there yet?: journeying along the cancer genetic information superhighway.我们到了吗？：在癌症基因信息高速公路上前行
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Editorial: The Fruits of the Genomic Revolution.社论：基因组革命的成果
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Functional annotation of HOT regions in the human genome: implications for human disease and cancer.人类基因组中HOT区域的功能注释：对人类疾病和癌症的影响
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Genetic variants in association studies--review of strengths and weaknesses in study design and current knowledge of impact on cancer risk.关联研究中的遗传变异——研究设计的优缺点及对癌症风险影响的现有知识综述。
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本文引用的文献
1
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.8q24癌症风险变异体rs6983267在结直肠癌中与MYC存在长程相互作用。
Nat Genet. 2009 Aug;41(8):882-4. doi: 10.1038/ng.403. Epub 2009 Jun 28.
2
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.位于8号染色体q24区域的常见结直肠癌易感单核苷酸多态性rs6983267具有增强Wnt信号传导的潜力。
Nat Genet. 2009 Aug;41(8):885-90. doi: 10.1038/ng.406. Epub 2009 Jun 28.
3
Genomewide association studies: history, rationale, and prospects for psychiatric disorders.全基因组关联研究：精神疾病的历史、原理及前景
Am J Psychiatry. 2009 May;166(5):540-56. doi: 10.1176/appi.ajp.2008.08091354. Epub 2009 Apr 1.
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A variant associated with nicotine dependence, lung cancer and peripheral arterial disease.一种与尼古丁依赖、肺癌和外周动脉疾病相关的变体。
Nature. 2008 Apr 3;452(7187):638-642. doi: 10.1038/nature06846.
5
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.肺癌的一个易感基因座定位于15号染色体长臂25区的烟碱型乙酰胆碱受体亚基基因。
Nature. 2008 Apr 3;452(7187):633-7. doi: 10.1038/nature06885.
6
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.标签单核苷酸多态性的全基因组关联扫描在15q25.1处鉴定出一个肺癌易感位点。
Nat Genet. 2008 May;40(5):616-22. doi: 10.1038/ng.109. Epub 2008 Apr 2.
7
A gene-centric approach to genome-wide association studies.一种以基因为中心的全基因组关联研究方法。
Nat Rev Genet. 2006 Nov;7(11):885-91. doi: 10.1038/nrg1962.
8
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men.混合线性模型定位法将8号染色体长臂24区鉴定为非裔美国男性前列腺癌的风险基因座。
Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):14068-73. doi: 10.1073/pnas.0605832103. Epub 2006 Aug 31.
9
Principal components analysis corrects for stratification in genome-wide association studies.主成分分析可校正全基因组关联研究中的分层现象。
Nat Genet. 2006 Aug;38(8):904-9. doi: 10.1038/ng1847. Epub 2006 Jul 23.
10
Structural variants: changing the landscape of chromosomes and design of disease studies.结构变异：改变染色体格局与疾病研究设计
Hum Mol Genet. 2006 Apr 15;15 Spec No 1:R57-66. doi: 10.1093/hmg/ddl057.
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