Eyigor C, Pirim A, Uyar M
Ege University Faculty of Medicine, Department of Anesthesiology, Pain Clinic, Bornova-Izmir, Turkey.
J BUON. 2010 Oct-Dec;15(4):715-9.
to investigate the impact of pancreatic cancer localization in relation to the response to different interventional pain management methods and determine the method most suitable for satisfactory pain control.
interventional pain management was carried out by sympathetic block or spinal analgesia. Patients were allocated into 2 groups according to the tumor localization, namely group 1 (n=61; patients with pancreatic cancer confined to the head of pancreas), and group 2 (n=55; patients with pancreatic cancer confined to the body or tail of pancreas).
among the patients who had interventional pain management, sufficient analgesia was achieved by sympathetic block in 9 of the 14 (64.3%) of them in group 1 and only in 3 of the 11 (27.3%) patients in group 2. Spinal analgesia was used in 5 of the 14 (35.7%) patients who required interventional pain management in group 1 and in 8 of the 11 (72.7%) patients in group 2 (p>0.05).
pain palliation could be achieved by sympathetic block in patients with cancer localized in the head of pancreas while patients with tumor localized in the body and tail experienced sufficient pain palliation by spinal analgesia rather than sympathetic block.
探讨胰腺癌的位置与不同介入性疼痛管理方法疗效之间的关系，并确定最适合实现满意疼痛控制的方法。
采用交感神经阻滞或脊髓镇痛进行介入性疼痛管理。根据肿瘤位置将患者分为两组，即第1组（n = 61；胰腺癌局限于胰头的患者）和第2组（n = 55；胰腺癌局限于胰体或胰尾的患者）。
在接受介入性疼痛管理的患者中，第1组14例中有9例（64.3%）通过交感神经阻滞实现了充分镇痛，而第2组11例中只有3例（27.3%）患者实现了充分镇痛。第1组14例需要介入性疼痛管理的患者中有5例（35.7%）使用了脊髓镇痛，第2组11例患者中有8例（72.7%）使用了脊髓镇痛（p>0.0）。
胰腺癌局限于胰头的患者可通过交感神经阻滞实现疼痛缓解，而肿瘤位于胰体和胰尾的患者通过脊髓镇痛而非交感神经阻滞可实现充分的疼痛缓解。
