Department of Clinical Neuroscience, Karolinska Institutet, Section of Psychiatry, Psychiatry Karolinska Northwest, Danderyd Hospital, SE-182 88 Stockholm, Sweden.
Eur J Obstet Gynecol Reprod Biol. 2011 Apr;155(2):161-5. doi: 10.1016/j.ejogrb.2010.12.012. Epub 2011 Jan 12.
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders affecting women of fertile age. The aim was to study whether PCOS has an effect on sexual functioning.
Women meeting the Rotterdam criteria for PCOS (n=49), and 49 age-matched controls identified from the population registry, were recruited. Sexual functioning was assessed by means of (i) an in-person, structured interview covering various aspects of sexuality, and (ii) the nine-item McCoy questionnaire of female sexual satisfaction. Participants also completed the Psychological General Well-Being Index.
Almost half the women with PCOS reported that the disorder had a great impact on their sex life. Despite having the same number of partners and about the same frequency of sexual intercourse, women with PCOS were generally less satisfied with their sex lives compared to the population-based controls. Within the group of women with PCOS, high body mass index had only a minor effect on sexual functioning, while the total serum level of testosterone correlated positively to sexual satisfaction. PCOS women scored numerically lower than controls on the McCoy total score, but this difference was not statistically significant.
Women with PCOS reported decreased satisfaction with their sex life. Sexual function should be taken into account in treatment trials of PCOS, which traditionally target only symptoms related to insulin resistance, overweight, and hirsutism.
多囊卵巢综合征（PCOS）是影响育龄妇女最常见的内分泌疾病之一。本研究旨在探讨 PCOS 是否对女性性功能有影响。
招募了符合 Rotterdam 标准的 PCOS 患者（n=49）和从人群登记处中匹配年龄的对照组（n=49）。通过（i）面对面的、涵盖性行为各个方面的结构化访谈，以及（ii）女性性满意度的九项 McCoy 问卷，评估了性健康。参与者还完成了心理一般健康指数问卷。
近一半的 PCOS 患者报告说，该疾病对她们的性生活有很大影响。尽管 PCOS 患者的伴侣数量相同，性生活频率也大致相同，但与基于人群的对照组相比，她们的性生活满意度普遍较低。在 PCOS 组中，高体重指数对性功能的影响较小，而总血清睾酮水平与性满意度呈正相关。PCOS 患者在 McCoy 总分上的得分低于对照组，但差异无统计学意义。
PCOS 患者报告说对性生活的满意度降低。在治疗 PCOS 的临床试验中应考虑性功能，传统的治疗方法仅针对与胰岛素抵抗、超重和多毛症相关的症状。
