Dick O E, Romanov S P, Nozdrachev A D
I P Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, Russia.
Bull Exp Biol Med. 2010 Oct;149(4):383-6. doi: 10.1007/s10517-010-0951-y.
The study tried to reveal the differences between physiological and pathological tremor appearing during maintenance of isometric force in healthy individual and parkinsonian patients with tremor. Six-level wavelet expansion was used presenting the tremor as a sum of smoothed (slow) component and high-frequency detailed components of 6 expansion levels. The differences in the high-frequency components were assessed by calculating the energetic parameters in the power spectrum of these components. These parameters make it possible not only to reliably distinguish the energetic spectra of the detail components of the physiological and pathological tremor, but also to correlate changes in patient state caused by drug treatment of parkinsonian trembling with the decrease in these parameters.
该研究试图揭示健康个体和患有震颤的帕金森病患者在维持等长力期间出现的生理性震颤和病理性震颤之间的差异。采用六级小波展开，将震颤表示为六个展开级别的平滑（缓慢）分量和高频细节分量之和。通过计算这些分量功率谱中的能量参数来评估高频分量的差异。这些参数不仅能够可靠地区分生理性和病理性震颤细节分量的能量谱，还能将帕金森病震颤药物治疗引起的患者状态变化与这些参数的降低联系起来。
