Institut de Chimie des Substances Naturelles, UPR 2301 CNRS, Centre de Recherches de Gif, Gif-sur-Yvette, France.
Chem Soc Rev. 2011 Apr;40(4):1926-36. doi: 10.1039/c0cs00095g. Epub 2011 Jan 13.
Catalytic C-H amination has recently emerged as a unique tool for the synthesis of amines. This tutorial review highlights the existing protocols catalyzed by metal complexes (rhodium, copper, ruthenium, manganese and palladium) allowing diastereo- and enantioselective C-H amination. Substrate-, catalyst- and reagent-controlled methodologies are detailed. They involve either catalytic nitrene C-H insertion or C-H activation.
催化 C-H 胺化最近作为一种独特的胺类合成工具而出现。本综述突出了金属配合物（铑、铜、钌、锰和钯）催化的现有反应方案，这些方案可以实现非对映选择性和对映选择性的 C-H 胺化。详细介绍了底物、催化剂和试剂控制的方法。它们涉及催化的氮宾 C-H 插入或 C-H 活化。
