Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
J Pediatr (Rio J). 2011 Jan-Feb;87(1):80-3. doi: 10.2223/JPED.2061. Epub 2011 Jan 13.
To assess the prevalence of middle ear alterations in cystic fibrosis (CF) patients.
In this descriptive study, 120 CF patients aged 5 months to 18 years were assessed by clinical history, otoscopy, and tympanometry. Data on P. aeruginosa colonization and parenteral and/or inhaled aminoglycoside use were also collected from medical charts.
Clinical history revealed absence of previous otitis media in 57% of patients. Tympanic membranes were normal in 94% of patients who underwent otoscopic evaluation; chronic otitis media was suggested in about 1% of the cases, otitis media with effusion (OME) in 2%, and Eustachian tube dysfunction in 3%. As for tympanometry, 91% of patients who underwent the exam showed normal results, OME was suggested in 2% of the cases, and Eustachian tube dysfunction in 7%.
There was a low prevalence rate of middle ear alterations in our series of CF patients. The use of aminoglycosides and colonization by P. aeruginosa did not influence the prevalence of middle ear alterations. Our results suggest that a detailed clinical history and a routine otoscopy evaluation may confirm or rule out most middle ear alterations in CF patients.
评估囊性纤维化（CF）患者中耳改变的发生率。
在这项描述性研究中，对 120 名年龄在 5 个月至 18 岁的 CF 患者进行了临床病史、耳镜检查和鼓室图测试。还从病历中收集了铜绿假单胞菌定植以及全身和/或吸入氨基糖苷类药物使用的数据。
临床病史显示，57%的患者以前没有中耳炎病史。接受耳镜检查的 94%患者鼓膜正常；约 1%的病例提示慢性中耳炎，2%的病例提示分泌性中耳炎，3%的病例提示咽鼓管功能障碍。对于鼓室图测试，91%接受检查的患者结果正常，2%的病例提示分泌性中耳炎，7%的病例提示咽鼓管功能障碍。
在我们的 CF 患者系列中，中耳改变的发生率较低。氨基糖苷类药物的使用和铜绿假单胞菌定植并不影响中耳改变的发生率。我们的结果表明，详细的临床病史和常规的耳镜检查可以确认或排除 CF 患者的大多数中耳改变。
