Rosado Pablo, Fernández Soledad, Junquera Luis, De Vicente Juan Carlos
Department of Oral and Maxillofacial Surgery, University of Oviedo, Central University Hospital, Oviedo, Spain.
J Craniofac Surg. 2011 Jan;22(1):348-50. doi: 10.1097/SCS.0b013e3181f7e169.
Although multiple synchronous malignancies of the same histological type have been described frequently in the upper aerodigestive tract, this is a less frequent phenomenon when dealing with tumors of different lineage. We present a case of a man who developed simultaneously an oral squamous cell carcinoma and chronic lymphocytic lymphoma of the palate without any previous risk factors. To the best of our knowledge, this is the first case well documented in the literature of synchronous oral squamous cell carcinoma and chronic lymphocytic lymphoma of the palate in the same sample. The presence of multiple primary malignancies of different histological types not only complicates the treatment but also worsens the prognosis of the patient.
尽管上消化道同一组织学类型的多原发同步恶性肿瘤已有频繁报道，但在处理不同谱系的肿瘤时，这种情况并不常见。我们报告一例男性患者，该患者在无任何既往危险因素的情况下，同时发生了口腔鳞状细胞癌和腭部慢性淋巴细胞淋巴瘤。据我们所知，这是文献中首例同一病例同时发生腭部同步口腔鳞状细胞癌和慢性淋巴细胞淋巴瘤的详细记录。不同组织学类型的多原发恶性肿瘤的存在不仅使治疗复杂化，而且还会使患者的预后恶化。
