Jamal C Y, Islam M M, Rahman S A
Department of Paediatric Haematology and Oncology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh.
Mymensingh Med J. 2011 Jan;20(1):134-7.
Acute lymphoblastic leukaemia (ALL) is the most common malignancy in children. Usually ALL children present with pallor, fever, bleeding, infection, lymphadenopathy and hapatosplenomegaly. Very rarely ALL patients may present with hypercalcaemia and osteolytic lesions. A five year old boy was referred and transferred to the paediatric ward of Bangabandhu Sheikh Mujib Medical University, Dhaka with the complaints of pain in the hip joint, generalized pain all over the body and very high calcium level. He was severely pale, the total leukocyte count was normal with normal distribution. Platelet count was also normal. There were some atypical lymphocytes. Radiology showed extensive osteolytic lesions. Considering all these findings, a bone marrow study was done, which was compatible with ALL. Flow-cytometry was also done and it confirmed the diagnosis as common ALL.
急性淋巴细胞白血病(ALL)是儿童中最常见的恶性肿瘤。通常,患ALL的儿童会出现面色苍白、发热、出血、感染、淋巴结病和肝脾肿大。ALL患者极少会出现高钙血症和溶骨性病变。一名5岁男孩因髋关节疼痛、全身疼痛和血钙水平极高的症状被转诊至达卡的孟加拉国国父谢赫·穆吉布医学大学儿科病房。他面色极度苍白,白细胞总数正常且分布正常。血小板计数也正常。有一些非典型淋巴细胞。放射学检查显示广泛的溶骨性病变。综合所有这些发现,进行了骨髓检查,结果与ALL相符。还进行了流式细胞术检查,确诊为普通型ALL。