Vasco Pablo Guisado, López Angel Ruedas
Internal Medicine department, University Hospital Ramón y Cajal, Colmenar Viejo Road km 9,1, Madrid, Spain.
Curr Drug Saf. 2011 Feb 1;6(1):59-60. doi: 10.2174/157488611794479955.
Varenicline is a drug specifically developed for smoking cessation. Gastrointestinal symptoms are among the most common side effects (nausea, vomiting, and constipation). Here, we described the case of a 75 year-old man who suffered from functional adynamic ileus while taking varenicline. Adynamic ileus is a rare condition on treatment with varenicline. Clinicals should be aware of this side effect due to it could lead to varenicline withdrawal and reconsideration of patient smoking cessation strategy.
伐尼克兰是一种专门为戒烟开发的药物。胃肠道症状是最常见的副作用之一(恶心、呕吐和便秘)。在此,我们描述了一名75岁男性在服用伐尼克兰时发生功能性动力缺乏性肠梗阻的病例。动力缺乏性肠梗阻是伐尼克兰治疗中罕见的情况。临床医生应意识到这种副作用,因为它可能导致停用伐尼克兰并重新考虑患者的戒烟策略。