Department of Women's and Children's Health, Obstetrics and Gynecology, Uppsala University, Uppsala, Sweden.
Acta Obstet Gynecol Scand. 2011 Feb;90(2):179-85. doi: 10.1111/j.1600-0412.2010.01026.x. Epub 2010 Dec 7.
To establish absolute- and relative-growth reference curves for the detection of intrauterine growth restriction from weekly self-administered symphysis-fundus (SF) measurements and to assess the influence of fetal sex, maternal obesity and parity.
Prospective longitudinal study.
Pregnant women from six primary antenatal care centres.
Three hundred women with singleton ultrasound dated pregnancies.
Weekly self-administered SF measurements from gestational week 25 until delivery were obtained. A linear mixed longitudinal model was used to estimate the absolute SF growth using the natural logarithm (lnSF). Relative lnSF growth was calculated as the lnSF measurement in one gestational week subtracted by the lnSF measurement in the previous gestational week. The influence of fetal sex, maternal obesity and parity was assessed in regression models and by a graphical display.
Absolute lnSF and relative lnSF growth curves and influence of fetal sex, maternal obesity and parity on these.
SF measurements from 191 women were used to establish an SF-growth reference. The absolute lnSF growth was influenced by maternal obesity, and for fetal sex and parity, borderline significance was recorded; while there was no evidence that the relative lnSF growth could depend on these variables.
Weekly self-administered SF measurements can be obtained and used to estimate SF growth. Relative growth of the lnSF height seems to be independent of fetal sex, maternal obesity and parity.
建立通过每周自我进行耻骨联合-宫底(SF)测量来检测宫内生长受限的绝对和相对生长参考曲线,并评估胎儿性别、母亲肥胖和产次的影响。
前瞻性纵向研究。
六个初级产前保健中心的孕妇。
300 名具有单胎超声妊娠的孕妇。
从妊娠 25 周到分娩每周进行自我管理的 SF 测量。使用线性混合纵向模型,使用自然对数(lnSF)估计绝对 SF 生长。相对 lnSF 生长计算为一个妊娠周的 lnSF 测量值减去前一个妊娠周的 lnSF 测量值。通过回归模型和图形显示评估胎儿性别、母亲肥胖和产次的影响。
绝对 lnSF 和相对 lnSF 生长曲线以及胎儿性别、母亲肥胖和产次对这些曲线的影响。
191 名妇女的 SF 测量值用于建立 SF 生长参考。绝对 lnSF 生长受母亲肥胖的影响,而对于胎儿性别和产次,记录到了边缘显著;而没有证据表明相对 lnSF 生长可能取决于这些变量。
每周自我进行 SF 测量可以获得并用于估计 SF 生长。lnSF 高度的相对生长似乎与胎儿性别、母亲肥胖和产次无关。