Christchurch Healthand Development Study, University of Otago, Christchurch, New Zealand.
J Am Acad Child Adolesc Psychiatry. 2011 Feb;50(2):132-140.e5. doi: 10.1016/j.jaac.2010.11.007. Epub 2011 Jan 6.
This study examined associations between age of menarche and psychosocial outcomes in early adulthood, including sexual behavior, mental health, criminal behavior, and education/employment, to identify the possible causal role of earlier age of menarche in increasing risks of adverse outcomes.
Data were gathered from 497 female members of a New Zealand longitudinal birth cohort. Outcome measures (to age 18 years) were as follows: pregnancy; sexually transmitted infection (STI); DSM-IV major depression, anxiety disorder, alcohol dependence and conduct disorder/ASPD; self-reported crime; convictions; leaving school without qualifications; and unemployment. Associations between age of menarche and outcome measures were then adjusted for confounding factors spanning family background, family functioning, and individual factors. Additional analyses examined sexual behavior outcomes to age 21, and all other outcomes to age 30 years.
Analyses showed that sexual behavior outcomes (pregnancy, STI) were significantly associated with age of menarche, even after controlling for confounding factors. Anxiety disorder was marginally (p < .10) associated with age of menarche. In addition, pregnancy during ages 18 to 21 years was significantly associated with age of menarche. There were no significant associations between age of menarche and outcomes at any other age (to age 30).
The study showed that females reaching menarche at an earlier age were at increased risk of early pregnancy, and STI by age 18. The present study found little evidence to suggest that age of menarche was related to mental health, criminal behavior, or education/employment outcomes for this cohort.
本研究探讨了初潮年龄与成年早期性行为、心理健康、犯罪行为和教育/就业等心理社会结局之间的关联,以确定初潮年龄较早与增加不良结局风险的可能因果关系。
本研究的数据来自新西兰一项纵向出生队列的 497 名女性成员。结局指标(至 18 岁)如下:妊娠;性传播感染(STI);DSM-IV 重性抑郁障碍、焦虑障碍、酒精依赖和品行障碍/反社会型人格障碍;自我报告的犯罪;定罪;未获得资格证书而辍学;以及失业。然后,在考虑了家庭背景、家庭功能和个体因素等混杂因素的情况下,调整了初潮年龄与结局指标之间的关联。进一步的分析检验了性行为结局至 21 岁,以及所有其他结局至 30 岁的情况。
分析表明,性行为结局(妊娠、STI)与初潮年龄显著相关,即使在控制了混杂因素后也是如此。焦虑障碍与初潮年龄略有相关(p<.10)。此外,18 至 21 岁时怀孕与初潮年龄显著相关。在任何其他年龄(至 30 岁),初潮年龄与结局均无显著关联。
本研究表明,初潮年龄较早的女性在 18 岁之前怀孕和感染 STI 的风险增加。本研究几乎没有证据表明,对于这一队列,初潮年龄与心理健康、犯罪行为或教育/就业结局相关。