7β-[1-(2-氨基噻唑-4-基)-1-环丙基甲酰胺基]头孢烯衍生物的合成及抗菌活性
Synthesis and antibacterial activity of 7 beta-[1-(2-aminothiazol-4-yl)-1-cyclopropanecarboxyamido]cephem derivatives.
作者信息
Nishimura S, Yasuda N, Sasaki H, Sakane K, Takaya T
机构信息
New Drug Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Osaka, Japan.
出版信息
J Antibiot (Tokyo). 1990 Oct;43(10):1278-85. doi: 10.7164/antibiotics.43.1278.
PMID:2124209
Abstract
The synthesis and antibacterial activity of several 7 beta-[1-(2-aminothiazol-4-yl)-1-cyclopropanecarboxyamido]cep hem derivatives (1) are described. The structure-activity relationships of 1 are also presented.
摘要
描述了几种7β-[1-(2-氨基噻唑-4-基)-1-环丙基甲酰胺基]头孢菌素衍生物(1)的合成及其抗菌活性。还介绍了1的构效关系。
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