Bonilla Silvana, Saps Miguel
Northwestern University, Chicago, IL, USA.
Clin Pediatr (Phila). 2011 May;50(5):396-401. doi: 10.1177/0009922810392773. Epub 2011 Jan 17.
Functional gastrointestinal disorders (FGIDs) are common. Diagnosis is based on the Rome criteria. It has been argued that performing endoscopies could help by providing reassurance and thus improve outcomes. This study was conducted to evaluate the impact of obtaining normal endoscopies in the outcome of children with FGIDs.
Medical records of patients diagnosed with abdominal pain related-FGIDs were reviewed. To assess the child's symptoms at follow-up, parents completed the Questionnaire on Pediatric Gastrointestinal Symptoms III (QPGS III). Primary outcome was presence of abdominal pain (AP) and secondary outcomes were AP severity.
A total of 301 patients were diagnosed with abdominal pain-related FGIDs. Overall, 62.6% reported persistence of AP and 37.4% were asymptomatic at follow-up. Among patients with endoscopies, 61% reported AP. Among patients without endoscopies, 64% were symptomatic (P = .76). AP frequency, AP intensity, and child's disability were similar in those with and without endoscopies.
The study does not suggest that a negative endoscopy improves the outcome of children with FGIDs.
功能性胃肠病(FGIDs)很常见。诊断基于罗马标准。有人认为进行内镜检查有助于消除疑虑,从而改善预后。本研究旨在评估内镜检查结果正常对FGIDs患儿预后的影响。
回顾诊断为腹痛相关FGIDs患者的病历。为评估随访时患儿的症状,家长填写了小儿胃肠道症状问卷III(QPGS III)。主要结局是腹痛(AP)的存在情况,次要结局是AP的严重程度。
共有301例患者被诊断为腹痛相关FGIDs。总体而言,62.6%的患者报告随访时仍有AP,37.4%无症状。在内镜检查患者中,61%报告有AP。未进行内镜检查的患者中,64%有症状(P = 0.76)。有或无内镜检查患者的AP频率、AP强度和患儿残疾情况相似。
该研究并不表明内镜检查结果阴性能改善FGIDs患儿的预后。