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Tramadol-induced adrenal insufficiency.

作者信息

Debono Miguel, Chan Sharon, Rolfe Christen, Jones T Hugh

出版信息

Eur J Clin Pharmacol. 2011 Aug;67(8):865-7. doi: 10.1007/s00228-011-0992-9. Epub 2011 Jan 18.

DOI:10.1007/s00228-011-0992-9
PMID:21243342
Abstract
摘要

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Tramadol-induced adrenal insufficiency.曲马多诱发的肾上腺功能不全。
Eur J Clin Pharmacol. 2011 Aug;67(8):865-7. doi: 10.1007/s00228-011-0992-9. Epub 2011 Jan 18.
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Epileptic seizure following IV tramadol in a patient with mental retardation and cerebellar ataxia.智力迟钝和小脑共济失调患者静脉注射曲马多后癫痫发作。
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Tramadol.曲马多
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The association of tramadol and morphine in the treatment of acute postoperative pain.曲马多与吗啡联合用于治疗急性术后疼痛。
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The effects of tramadol on postoperative nausea, vomiting and headache after ENT surgery. A placebo-controlled comparison with equipotent doses of nalbuphine and pethidine.曲马多对耳鼻喉科手术后恶心、呕吐及头痛的影响。与等效剂量纳布啡和哌替啶的安慰剂对照比较。
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Opioid-induced adrenal insufficiency: diagnostic and management considerations.阿片类药物引起的肾上腺功能不全：诊断和治疗注意事项。
Front Endocrinol (Lausanne). 2024 Feb 27;14:1280603. doi: 10.3389/fendo.2023.1280603. eCollection 2023.
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Iatrogenic adrenal insufficiency in adults.成人医源性肾上腺功能不全
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Idiopathic isolated adrenocorticotropic hormone deficiency: a systematic review of a heterogeneous and underreported disease.

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The effects of opioids and opioid analogs on animal and human endocrine systems.阿片类药物和阿片类药物类似物对动物和人类内分泌系统的影响。
Endocr Rev. 2010 Feb;31(1):98-132. doi: 10.1210/er.2009-0009. Epub 2009 Nov 10.
2
Secondary adrenal failure and secondary amenorrhoea following hydromorphone treatment.氢吗啡酮治疗后的继发性肾上腺功能减退和继发性闭经。
Clin Endocrinol (Oxf). 2007 Apr;66(4):604-5. doi: 10.1111/j.1365-2265.2007.02779.x.
3
The mu-opioid receptor polymorphism A118G predicts cortisol responses to naloxone and stress.
特发性孤立性促肾上腺皮质激素缺乏症：一种异质性且报道不足疾病的系统评价。
Pituitary. 2024 Feb;27(1):23-32. doi: 10.1007/s11102-023-01366-9. Epub 2023 Dec 27.
4
A Closer Look at Opioid-Induced Adrenal Insufficiency: A Narrative Review.深入探讨阿片类药物引起的肾上腺功能不全：一项叙述性综述。
Int J Mol Sci. 2023 Feb 26;24(5):4575. doi: 10.3390/ijms24054575.
5
Gonadotoxic effect of tramadol administration: A prospective controlled study.曲马多给药的性腺毒性作用：一项前瞻性对照研究。
Arab J Urol. 2021 Nov 26;20(1):54-60. doi: 10.1080/2090598X.2021.2002634. eCollection 2022.
6
Less Well-Known Consequences of the Long-Term Use of Opioid Analgesics: A Comprehensive Literature Review.长期使用阿片类镇痛药的不那么为人知的后果：全面文献综述。
Drug Des Devel Ther. 2022 Jan 18;16:251-264. doi: 10.2147/DDDT.S342409. eCollection 2022.
7
Opioids and pituitary function: expert opinion.阿片类药物与垂体功能：专家意见。
Pituitary. 2022 Feb;25(1):52-63. doi: 10.1007/s11102-021-01202-y. Epub 2022 Jan 23.
8
Prevalence of Opioid-Induced Adrenal Insufficiency in Patients Taking Chronic Opioids.慢性阿片类药物使用者中阿片类药物诱导的肾上腺功能不全的患病率。
J Clin Endocrinol Metab. 2020 Oct 1;105(10):e3766-75. doi: 10.1210/clinem/dgaa499.
9
Effect of tramadol dependence on male sexual dysfunction.曲马多依赖对男性性功能障碍的影响。
Interdiscip Toxicol. 2019 Dec;12(4):157-162. doi: 10.2478/intox-2019-0019. Epub 2020 Apr 30.
10
Opioid-induced hypoadrenalism resulting in fasting hypoglycaemia.阿片类药物引起的肾上腺功能减退导致空腹低血糖症。
BMJ Case Rep. 2019 Dec 11;12(12):e230551. doi: 10.1136/bcr-2019-230551.
μ-阿片受体基因多态性A118G可预测皮质醇对纳洛酮和应激的反应。
Neuropsychopharmacology. 2006 Jan;31(1):204-11. doi: 10.1038/sj.npp.1300856.
4
Chronic fentanyl application induces adrenocortical insufficiency.长期应用芬太尼会导致肾上腺皮质功能不全。
J Intern Med. 2005 May;257(5):478-80. doi: 10.1111/j.1365-2796.2005.01483.x.
5
Tramadol produces outward currents by activating mu-opioid receptors in adult rat substantia gelatinosa neurones.曲马多通过激活成年大鼠脊髓背角胶状质神经元中的μ-阿片受体产生外向电流。
Br J Pharmacol. 2005 Jul;145(5):602-7. doi: 10.1038/sj.bjp.0706225.
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Patients with chronic pain and abnormal pituitary function require investigation.患有慢性疼痛和垂体功能异常的患者需要进行检查。
Lancet. 2003 Jun 28;361(9376):2203-4. doi: 10.1016/s0140-6736(03)13775-0.
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Endocrine consequences of long-term intrathecal administration of opioids.长期鞘内注射阿片类药物的内分泌后果。
J Clin Endocrinol Metab. 2000 Jun;85(6):2215-22. doi: 10.1210/jcem.85.6.6615.
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Molecular pharmacology of the opioid receptors.阿片受体的分子药理学
Pharmacol Ther. 1995;68(3):343-64. doi: 10.1016/0163-7258(95)02011-x.
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Action of opioid peptides on the rat adrenal cortex: stimulation of steroid secretion through a specific mu opioid receptor.阿片样肽对大鼠肾上腺皮质的作用：通过特定的μ阿片受体刺激类固醇分泌。
J Endocrinol. 1995 Mar;144(3):503-10. doi: 10.1677/joe.0.1440503.
10
Impaired circadian rhythmicity of beta-lipotrophin, beta-endorphin and ACTH in heroin addicts.海洛因成瘾者中β-促脂素、β-内啡肽和促肾上腺皮质激素的昼夜节律受损。
Acta Endocrinol (Copenh). 1984 Feb;105(2):149-55. doi: 10.1530/acta.0.1050149.