Palma Stefan A, Metnitz Philipp G H, Kamolz Lars-Peter, Frey Manfred, Druml Wilfred
Universitätsklinik für Anästhesiologie, All gemeine Intensivmedizin und Schmerztherapie der Medizinischen Universität Wien, Allgemeines Krankenhaus der Stadt Wien.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2011 Jan;46(1):12-9. doi: 10.1055/s-0030-1270554. Epub 2011 Jan 17.
Acute renal failure (ARF) is a common and dangerous complication in intensive care medicine. Especially critical ill patients, who are suffering from major burns, have a high risk to develop ARF as a consequence of their trauma. Many factors, including the trauma itself, the damage of soft tissue and consecutive rhabdomyolysis, the development of the burn illness and therapeutic interventions play also a major role in this context. These circumstances have a major impact on the morbidity and mortality of severely burned patients. The aim of this manuscript is to review the reasons for the development of an ARF in burn patients as well as its consequences; moreover it highlights potential strategies to avoid ARF in critically ill burned patients.
急性肾衰竭(ARF)是重症监护医学中常见且危险的并发症。尤其是患有大面积烧伤的危重症患者,因其创伤而发生ARF的风险很高。许多因素,包括创伤本身、软组织损伤及随后的横纹肌溶解、烧伤病情的发展以及治疗干预措施,在这方面也起着重要作用。这些情况对严重烧伤患者的发病率和死亡率有重大影响。本文的目的是回顾烧伤患者发生ARF的原因及其后果;此外,还强调了避免危重症烧伤患者发生ARF的潜在策略。