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[精神药物 - 抗惊厥药和抗精神病药在慢性疼痛患者治疗中的特殊重要性]

[Psychotropic drugs - The special importance of anticonvulsants and neuroleptics in treatment of patients with chronic pain].

作者信息

Brinkers Michael, Petz Tobias, Hoffmeyer Dieter

机构信息

Klinik für Anästhesiologie und Intensivtherapie, Universität Magdeburg.

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2011 Jan;46(1):20-7. doi: 10.1055/s-0030-1270555. Epub 2011 Jan 17.

Abstract

Therapy by psychotropic drugs is bound to limited indications, which are partially changing. By an extent literary research in pubmed and Cochrane especially corresponding articles of the past 10 years were proofed. So antidepressants were continually seldom given to nociceptor pain. While on the other side anticonvulsants are to be given in the case of neuropathic pain of defined quality, it will be looked for new applications for these drugs. Particularly hitherto existing difficult indications as fibromyalgia were investigated as possible indication for anticonvulsants. At least neuroleptics can be used for very difficult, resistant and bizarre pains such as cenesthesias.

摘要

精神药物治疗有其特定的适用范围,且部分适用范围正在发生变化。通过在PubMed和Cochrane上进行的文献研究,特别是对过去10年的相关文章进行了查证。因此,抗抑郁药很少用于伤害性疼痛。另一方面,对于特定类型的神经性疼痛,抗惊厥药是适用的,并且人们正在探索这些药物的新应用。特别是,对纤维肌痛等迄今难以治疗的疾病,研究了抗惊厥药作为可能的治疗方法。至少,抗精神病药可用于治疗非常严重、难治且怪异的疼痛,如躯体感觉异常。

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