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连枷胸发病率和死亡率的影响因素:前后位与侧位的比较

Factors affecting morbidity and mortality in flail chest: comparison of anterior and lateral location.

作者信息

Kilic D, Findikcioglu A, Akin S, Akay T H, Kupeli E, Aribogan A, Hatipoglu A

机构信息

Department of Thoracic Surgery, Baskent University, Ankara, Turkey.

出版信息

Thorac Cardiovasc Surg. 2011 Feb;59(1):45-8. doi: 10.1055/s-0030-1250597. Epub 2011 Jan 17.

Abstract

OBJECTIVE

Flail chest is most often accompanied by significant underlying pulmonary parenchymal injuries and may constitute a life-threatening thoracic injury. In this study we evaluated the treatment modalities for flail chest depending on the effect of trauma localization on mortality and morbidity.

METHODS

Between 2003 and 2008, 23 patients (20 males/3 females) were treated for flail chest. Location of the trauma in the chest wall, mechanical ventilation support, prognosis and injury severity score (ISS) were recorded for all patients. Mechanical ventilation support was given in 14 patients (60.8 %), and 12 of these 14 patients required subsequent tracheostomy. Internal fixation was used in 3 patients.

RESULTS

The major cause of flail chest was a car crash in 18 of 23 patients (76 %). Median ISS was 62.8 for all patients. The patients with flail chest who had bilateral costochondral separation (anterior chest location) (group I, n = 10) had a significantly higher ISS than those with single-side posterolateral flail chest (group II, n = 13; ISS: 70/55; P = 0.02). The need for mechanical ventilation support was also higher in the group with bilateral costochondral separation. Morbidity was higher in group I than in group II ( P = 0.198), and mortality was also significantly higher in group I ( P = 0.08). Patients with a cranial trauma and flail chest had a higher mortality (19 %) than patients with only flail chest (no mortality). The mean ISS was 75 for patients with cranial trauma and flail chest and 55.7 ( P = 0.001) for patients with only flail chest. Sepsis and subarachnoid bleeding were the major causes of mortality. The mean ISS was 54.5 for patients under the age of 55 (n = 14) whereas it was 69.4 in those aged 55 and over (n = 9; P = 0.034). Mortality in the older group was also higher (33 % versus 7 %; P = 0.02).

CONCLUSION

Early intubation and mechanical ventilation is of paramount importance in patients with flail chest. However, prolonged mechanical ventilation is associated with a poor outcome. Tracheotomy and frequent flexible bronchoscopy are an effective pulmonary toilet. Advanced age was a major risk factor for flail chest trauma mortality, together with the severity of the injury. When cranial trauma was accompanied by flail chest, mortality and morbidity rates increased. Bilateral costochondral separation also increased the risk of morbidity and the need for mechanical ventilation in patients with flail chest.

摘要

目的

连枷胸常伴有严重的潜在肺实质损伤,可能构成危及生命的胸部损伤。在本研究中,我们根据创伤部位对死亡率和发病率的影响评估了连枷胸的治疗方式。

方法

2003年至2008年期间,23例(20例男性/3例女性)连枷胸患者接受了治疗。记录所有患者胸壁创伤的位置、机械通气支持情况、预后和损伤严重程度评分(ISS)。14例患者(60.8%)接受了机械通气支持,其中12例随后需要气管切开术。3例患者使用了内固定。

结果

23例患者中有18例(76%)连枷胸的主要原因是车祸。所有患者的ISS中位数为62.8。双侧肋软骨分离(前胸位置)的连枷胸患者(I组,n = 10)的ISS显著高于单侧后外侧连枷胸患者(II组,n = 13;ISS:70/55;P = 0.02)。双侧肋软骨分离组对机械通气支持的需求也更高。I组的发病率高于II组(P = 0.198),I组的死亡率也显著更高(P = 0.08)。伴有颅脑创伤和连枷胸的患者死亡率(19%)高于仅患有连枷胸的患者(无死亡)。伴有颅脑创伤和连枷胸的患者平均ISS为75,仅患有连枷胸的患者平均ISS为55.7(P = 0.001)。脓毒症和蛛网膜下腔出血是主要死亡原因。55岁以下患者(n = 14)的平均ISS为54.5,而55岁及以上患者(n = 9)的平均ISS为69.4(P = 0.034)。老年组的死亡率也更高(33%对7%;P = 0.02)。

结论

对于连枷胸患者,早期插管和机械通气至关重要。然而,长时间的机械通气与不良预后相关。气管切开术和频繁的可弯曲支气管镜检查是有效的肺部清洁措施。高龄是连枷胸创伤死亡的主要危险因素,同时还有损伤的严重程度。当颅脑创伤伴有连枷胸时,死亡率和发病率会增加。双侧肋软骨分离也增加了连枷胸患者的发病风险和对机械通气的需求。

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