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水凝胶微球保护的活细菌静电纺丝制备聚合物/细菌复合纳米纤维非织造布。

Polymer/bacteria composite nanofiber non-wovens by electrospinning of living bacteria protected by hydrogel microparticles.

机构信息

Philipps-Universität Marburg, Department of Chemistry and Scientific Center of Materials Science, Hans-Meerwein-Str., D-35032 Marburg, Germany.

出版信息

Macromol Biosci. 2011 Mar 10;11(3):333-7. doi: 10.1002/mabi.201000310. Epub 2011 Jan 17.

Abstract

Physically crosslinked PVA-hydrogel microparticles are utilized for encapsulation of E. coli and M. luteus. The bacteria survive dry storage or treatment with bacteria-hostile organic solvents significantly better than unprotected bacteria as proven by culture-test experiments. The bacteria-protecting PVA microparticles are available for standard polymer-solution-processing techniques, as exemplarily shown by co-electrospinning of living bacteria encapsulated in dry PVA-hydrogel microparticles together with PVB-, PLLA-, and PCL-form organic solvents.

摘要

物理交联的聚乙烯醇水凝胶微球被用于包封大肠杆菌和藤黄微球菌。通过培养试验证明,与未经保护的细菌相比,这些细菌在干燥储存或用细菌敌对的有机溶剂处理后,存活能力显著提高。如通过共静电纺丝将干燥的聚乙烯醇水凝胶微球中包封的活细菌与 PVB、PLLA 和 PCL 形式的有机溶剂一起进行标准的聚合物溶液处理技术所示,这些细菌保护用的聚乙烯醇微球可适用于多种技术。

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