Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
J Org Chem. 2011 Feb 18;76(4):1163-6. doi: 10.1021/jo1021772. Epub 2011 Jan 18.
Upon photoirradiation of o-alkynylaryl isocyanides in the presence of iodine, the intramolecular cyclization of o-alkynylaryl isocyanides proceeds to afford the corresponding 2,4-diiodoquinolines in good yields. 2,4-Diiodoquinolines can be employed in transition metal-catalyzed cross-coupling reactions.
在碘存在下光照射邻炔基芳基异氰化物时，邻炔基芳基异氰化物发生分子内环化反应，以良好的收率得到相应的 2,4-二碘喹啉。2,4-二碘喹啉可用于过渡金属催化的交叉偶联反应。
