van der Spuy Dorothy A, Cader Shihaam, van der Spuy Gian D, Westwood Anthony T
Division of Molecular Biology and Human Genetics, Stellenbosch University, Tygerberg, South Africa.
J Paediatr Child Health. 2011 May;47(5):282-6. doi: 10.1111/j.1440-1754.2010.01954.x. Epub 2011 Jan 18.
To determine the nutritional status of children attending a cystic fibrosis clinic in a tertiary hospital in South Africa and compare it to previously reported 10-year rates.
Weights and heights were measured of 69 (37 male and 32 female) children aged between 1 year and 18 years. Expected weight-for-age, expected height-for-age, expected weight-for-height and body mass index (BMI) were compared with international standards for underweight, stunting, wasting and BMI goal.
The nutritional status of the patients has improved over the last 10 years, most significantly for wasting, which decreased from 58.3% in 1996 to 15.9% in 2006 (95% confidence interval (CI), 1.315-14.09, P < 0.05). Fifty-two percent of the children were underweight in 2006, compared with 66.7% in 1996 (95% CI, 0.044-13.96, P < 0.05). Stunting was found in 31.9% of the current sample. Females over 15 years had expected weight-for-age 25.9% lower than those between 10 years and 15 years, while no difference was found between the male age groups. Female height-for-age was 7.06 percentage points greater than males between 10 years and 15 years (95% CI, 2.16-11.96, P < 0.01). Males between 10 years and 15 years had significantly lower BMIs than the corresponding female group. Coloured patients had significantly lower BMIs than white patients in all age groups.
These children demonstrated continuing improvement in nutritional status, although deficits remain. The normalisation of mean weight-for-age and weight-for-height with far fewer wasted patients is encouraging. Interventions are needed in some areas to ensure that all children show progress.
确定南非一家三级医院囊性纤维化门诊儿童的营养状况，并将其与之前报道的10年数据进行比较。
对69名年龄在1岁至18岁之间的儿童（37名男性和32名女性）进行身高和体重测量。将预期年龄别体重、预期年龄别身高、预期身高别体重和体重指数（BMI）与国际消瘦、发育迟缓、消瘦和BMI目标标准进行比较。
在过去10年中，患者的营养状况有所改善，最显著的是消瘦情况，从1996年的58.3%降至2006年的15.9%（95%置信区间（CI），1.315 - 14.09，P < 0.05）。2006年，52%的儿童体重不足，而1996年为66.7%（95% CI，0.044 - 13.96，P < 0.05）。在当前样本中，31.9%的儿童存在发育迟缓。15岁以上女性的预期年龄别体重比10至15岁女性低25.9%，而男性不同年龄组之间未发现差异。10至15岁女性的年龄别身高比男性高7.06个百分点（95% CI，2.16 - 11.96，P < 0.01）。10至15岁男性的BMI显著低于相应女性组。在所有年龄组中，有色人种患者的BMI显著低于白人患者。
这些儿童的营养状况持续改善，尽管仍存在不足。平均年龄别体重和身高别体重的正常化以及消瘦患者数量的大幅减少令人鼓舞。在某些领域需要进行干预，以确保所有儿童都取得进步。
