Department of Surgery, University of Iowa Carver College of Medicine, Iowa City, IA, Iowa.
Ann Surg Oncol. 2011 Jun;18(6):1729-33. doi: 10.1245/s10434-010-1544-8. Epub 2011 Jan 19.
After thyroid lobectomy, many patients require ongoing care. This study sought to quantify the rates of surveillance and intervention after thyroid lobectomy.
One hundred one consecutive patients who underwent a thyroid lobectomy for nodular disease were evaluated. Clinical and follow-up data were obtained by a review of patient charts and included an evaluation of resource utilization related to thyroid disease.
Nineteen patients required completion thyroidectomy for thyroid cancer, and 11 had hypothyroidism before lobectomy. Of the remaining evaluable patients, 30 (42.2%) of 71 required thyroid hormone replacement after lobectomy, with 24 patients having elevated thyroid-stimulating hormone and 6 suppression of nodules in the contralateral lobe. The likelihood of thyroid hormone replacement demonstrated a trend with a contralateral nodule (9 of 14 vs. 21 of 57, P = 0.06) and a significant association with thyroiditis on surgical pathology (10 of 11 vs. 20 of 60, P < 0.001). Of the 82 patients who did not undergo completion lobectomy, 10 (12%) of 82 underwent postoperative fine-needle aspiration of the contralateral lobe, and 25 (30%) of 82 were followed with ultrasound surveillance. Only 27% of patients treated with lobectomy required no further surveillance or intervention. There were no instances of permanent recurrent laryngeal nerve injury.
After thyroid lobectomy, most patients require continued surveillance and intervention. With a near-zero complication rate, total thyroidectomy may be a more effective and efficient option for management of nodular thyroid disease.
甲状腺叶切除术后,许多患者需要持续护理。本研究旨在量化甲状腺叶切除术后的监测和干预率。
评估了 101 例因结节性疾病行甲状腺叶切除术的连续患者。通过回顾患者病历获得临床和随访数据,包括与甲状腺疾病相关的资源利用评估。
19 例患者因甲状腺癌需要完成甲状腺切除术,11 例患者在叶切除术前患有甲状腺功能减退症。在可评估的剩余患者中,30 例(71 例中的 42.2%)在叶切除术后需要甲状腺激素替代治疗,其中 24 例甲状腺刺激激素升高,6 例对侧叶结节抑制。甲状腺激素替代的可能性与对侧结节呈趋势(9/14 例与 21/57 例,P=0.06),与手术病理上的甲状腺炎有显著关联(10/11 例与 20/60 例,P<0.001)。在未行全叶切除术的 82 例患者中,10 例(82 例中的 12%)行对侧叶术后细针抽吸,25 例(82 例中的 30%)行超声监测。仅 27%的接受叶切除术治疗的患者无需进一步监测或干预。无永久性喉返神经损伤的病例。
甲状腺叶切除术后,大多数患者需要持续监测和干预。全甲状腺切除术并发症发生率接近零,可能是结节性甲状腺疾病更有效和有效的治疗选择。