de'Clari F, Nikolic J, Genoni M, Riva A, Moccetti T
Unité de soins intensifs et clinique médicale, Ospedale civico, Lugano.
Schweiz Med Wochenschr. 1990 Dec 8;120(49):1880-3.
Gonococcal endocarditis, although extremely rare, is increasing in frequency, particularly among young exposed patients. It has a distinct predilection for aortic and mitral valve involvement and tends to cause rapid valvular destruction and acute heart failure. Blood cultures are often negative during the first (3 to 31) days. Echocardiography with Doppler is helpful in detecting valvular vegetations, regurgitation and signs of hemodynamic deterioration. Early antibiotic treatment may stabilize the hemodynamic situation only in mitral but not in aortic valve involvement, which necessitates prompt valvular replacement in the event of perforation and/or annulus abscess. Gonococcal endocarditis should be the first item to be excluded in cases of fever with systemic symptoms in young people with a history of sex-transmitted disease. We present a typical case.
淋菌性心内膜炎虽然极为罕见,但发病率正在上升,尤其是在有接触史的年轻患者中。它明显倾向于累及主动脉瓣和二尖瓣,往往会导致瓣膜迅速破坏和急性心力衰竭。在最初的(3至31)天内血培养常为阴性。多普勒超声心动图有助于检测瓣膜赘生物、反流及血流动力学恶化的迹象。早期抗生素治疗仅在二尖瓣受累时可能稳定血流动力学状况,而在主动脉瓣受累时则不然,一旦发生穿孔和/或瓣环脓肿,就需要及时进行瓣膜置换。对于有性传播疾病史的年轻人出现发热伴全身症状的病例,应首先排除淋菌性心内膜炎。我们报告一例典型病例。