马丘波病毒的结构多肽
Structural polypeptides of Machupo virus.
作者信息
Gangemi J D, Rosato R R, Connell E V, Johnson E M, Eddy G A
出版信息
J Gen Virol. 1978 Oct;41(1):183-8. doi: 10.1099/0022-1317-41-1-183.
The structural proteins of an arenavirus pathogen, Machupo virus, were compared to the structural proteins of two previously characterized non-pathogenic arenaviruses, Pichinde and Tacaribe, in SDS-polyacrylamide gels. Similarities in mol. wt. of the major structural proteins from both pathogenic and non-pathogenic viruses were apparent; however, some differences in the number of glycosylation properties of minor proteins were observed. Machupo virions contain two major protein species. The most prominent is a non-glycosylated protein with a mol. wt. of 68000, while the other was glycosylated protein with a mol. wt. of 41000. Minor amounts of other proteins (mol. wt. 84000, 74000, 50000 and 15000) and a glycolipid were also observed.
在十二烷基硫酸钠-聚丙烯酰胺凝胶中，将马丘波病毒（一种沙粒病毒病原体）的结构蛋白与另外两种先前已鉴定的非致病性沙粒病毒——皮钦德病毒和塔卡里贝病毒的结构蛋白进行了比较。致病性和非致病性病毒的主要结构蛋白在分子量上的相似性很明显；然而，在次要蛋白的糖基化特性数量上观察到了一些差异。马丘波病毒粒子包含两种主要的蛋白种类。最突出的是一种分子量为68000的非糖基化蛋白，而另一种是分子量为41000的糖基化蛋白。还观察到少量其他蛋白（分子量分别为84000、74000、50000和15000）以及一种糖脂。
Zotero 插件