Reeder B A, Shah C P, Williams D A
Can Fam Physician. 1988 Jul;34:1535-9.
Native Indians in the Sioux Lookout Zone of Northwestern Ontario experience lower mortality from cardiovascular diseases than does the general Canadian population, despite a higher prevalence of such risk factors as smoking, obesity, and hypertension. To investigate whether this pattern may be related to the population distribution of serum lipids, the authors conducted a cross-sectional survey. One hundred and ninety-three registered Indians, 18 years of age or older, living in four isolated villages in the Zone were interviewed and examined. Age, sex, height, and weight were determined. A blood specimen was analysed for fasting serum triglyceride, cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol. In relation to reference populations, the distribution of serum triglyceride, cholesterol, and LDL cholesterol values is similar to that reported in other Native and non-Native populations, while that of HDL cholesterol is higher. Elevated levels of HDL cholesterol in this population may play a role in protecting it from a higher incidence of coronary heart disease.