Lubin S
Can Fam Physician. 1988 Oct;34:2277-80.
The scientific evidence for the efficacy of oxygen therapy in acute hypoxemia is limited. In chronic hypoxemia continuous oxygen therapy appears to decrease mortality. Current indications for oxygen treatment are PaO(2) less than 60 in acute hypoxemia and less than 55 in chronic hypoxemia. Physical and physiological hazards of oxygen are reviewed. Three syndromes of pulmonary oxygen toxicity are described: tracheobronchitis, adult respiratory distress syndrome, and bronchopulmonary dysplasia.
氧疗对急性低氧血症疗效的科学证据有限。在慢性低氧血症中,持续氧疗似乎可降低死亡率。目前氧疗的指征是急性低氧血症时动脉血氧分压(PaO₂)低于60,慢性低氧血症时低于55。本文综述了氧的物理和生理危害。描述了三种肺氧中毒综合征:气管支气管炎、成人呼吸窘迫综合征和支气管肺发育不良。