氧气的合理使用。
The appropriate use of oxygen.
作者信息
Lubin S
出版信息
Can Fam Physician. 1988 Oct;34:2277-80.
Abstract
The scientific evidence for the efficacy of oxygen therapy in acute hypoxemia is limited. In chronic hypoxemia continuous oxygen therapy appears to decrease mortality. Current indications for oxygen treatment are PaO(2) less than 60 in acute hypoxemia and less than 55 in chronic hypoxemia. Physical and physiological hazards of oxygen are reviewed. Three syndromes of pulmonary oxygen toxicity are described: tracheobronchitis, adult respiratory distress syndrome, and bronchopulmonary dysplasia.
摘要
氧疗对急性低氧血症疗效的科学证据有限。在慢性低氧血症中，持续氧疗似乎可降低死亡率。目前氧疗的指征是急性低氧血症时动脉血氧分压（PaO₂）低于60，慢性低氧血症时低于55。本文综述了氧的物理和生理危害。描述了三种肺氧中毒综合征：气管支气管炎、成人呼吸窘迫综合征和支气管肺发育不良。
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本文引用的文献
1
Experiments on acclimatisation to reduced atmospheric pressure.关于适应低气压的实验。
J Physiol. 1919 Dec 3;53(3-4):181-206. doi: 10.1113/jphysiol.1919.sp001870.
2
Oxygen therapy. Side effects and toxicity.氧疗。副作用与毒性。
Am Rev Respir Dis. 1980 Nov;122(5 Pt 2):61-9. doi: 10.1164/arrd.1980.122.5P2.61.
3
Oxygen therapy for surgical patients.外科患者的氧疗
Am Rev Respir Dis. 1980 Nov;122(5 Pt 2):37-44. doi: 10.1164/arrd.1980.122.5P2.37.
4
Hypoxemia and O2 therapy.
Am Rev Respir Dis. 1982 Oct;126(4):729-33. doi: 10.1164/arrd.1982.126.4.729.
5
Acute and long-term ventilatory effects of hyperoxia in the adult sleep apnea syndrome.高氧对成人睡眠呼吸暂停综合征的急性和长期通气影响。
Am Rev Respir Dis. 1982 Feb;125(2):175-80. doi: 10.1164/arrd.1982.125.2.175.
6
Psychologic effects of continuous and nocturnal oxygen therapy in hypoxemic chronic obstructive pulmonary disease.持续及夜间氧疗对低氧血症型慢性阻塞性肺疾病的心理影响
Arch Intern Med. 1983 Oct;143(10):1941-7.
7
The role of long-term continuous oxygen administration in patients with chronic airway obstruction with hypoxemia.长期持续吸氧在慢性气道阻塞伴低氧血症患者中的作用。
Ann Intern Med. 1967 Apr;66(4):639-50. doi: 10.7326/0003-4819-66-4-639.
8
Pulomonary edema in the course of a blood transfusion without overloading the circulation.
Dis Chest. 1966 Dec;50(6):619-23. doi: 10.1378/chest.50.6.619.
9
Reversal of pulmonary hypertension by prolonged oxygen administration to patients with chronic bronchitis.通过对慢性支气管炎患者长期给予氧气来逆转肺动脉高压。
Circ Res. 1968 Jul;23(1):147-57. doi: 10.1161/01.res.23.1.147.
10
Long-term continuous oxygen therapy in chronic airway obstruction. Mortality in relationship to cor pulmonale, hypoxia, and hypercapnia.慢性气道阻塞的长期持续氧疗。与肺心病、低氧血症和高碳酸血症相关的死亡率。
Ann Intern Med. 1970 May;72(5):621-6. doi: 10.7326/0003-4819-72-5-621.
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