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比较瑞芬太尼复合丙泊酚、七氟醚和地氟醚用于鼻内镜鼻窦手术的手术条件。

Comparison of surgical condition in endoscopic sinus surgery using remifentanil combined with propofol, sevoflurane, or desflurane.

机构信息

Department of Anesthesiology and Pain Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.

出版信息

Korean J Anesthesiol. 2010 Dec;59(6):377-82. doi: 10.4097/kjae.2010.59.6.377. Epub 2010 Dec 31.

Abstract

BACKGROUND

Various maneuvers are commonly used to achieve the ideal operative field necessary for successful endoscopic sinus surgery (ESS). There are a few contradictory reports on this subject and the consensus is that propofol anesthesia results in a better or similar surgical field and less or similar amount of bleeding than volatile anesthesia. The aim of this study was to compare the surgical field in patients in whom intravenous anesthesia is used as opposed to balanced general anesthesia.

METHODS

SIXTY PATIENTS UNDERGOING ESS WERE RANDOMLY ASSIGNED INTO THREE GROUPS, EACH OF WHICH USED A DIFFERENT TYPE OF ANESTHESIA: propofol/remifentanil (PRO/REM) group, sevoflurane/remifentanil (SEV/REM) group, and desflurane/remifentanil (DES/REM) group. We aimed to maintain the intraoperative mean blood pressure (MBP) at 65 mmHg and the heartrate (HR) at about 75 beats per minute. The quality of visibility of the surgical field was graded, using a validated scoring system, 60 minutes after the start of the operation.

RESULTS

All groups had a similar MBP and mean HR at 60 minutes after the operation started. There was no significant differences among the three groups for surgical grade score (P = 0.83).

CONCLUSIONS

In this comparative study of three anesthetic combinations (PRO/REM, SEV/REM, and DES/REM) in patients undergoing ESS with controlled BP and HR, we did not observe any significant differences in the surgical grade scores.

摘要

背景

为了实现内镜鼻窦手术(ESS)成功所需的理想手术视野,各种手法被广泛应用。关于这一主题有一些相互矛盾的报道,共识是异丙酚麻醉会带来更好或相似的手术视野,以及更少或相似量的出血,而挥发性麻醉则不然。本研究旨在比较静脉麻醉与平衡全身麻醉在患者中的手术视野。

方法

60 例接受 ESS 的患者被随机分为三组,每组使用不同类型的麻醉:异丙酚/瑞芬太尼(PRO/REM)组、七氟醚/瑞芬太尼(SEV/REM)组和地氟醚/瑞芬太尼(DES/REM)组。我们旨在维持术中平均血压(MBP)在 65mmHg 左右,心率(HR)在每分钟 75 次左右。手术开始后 60 分钟,使用经过验证的评分系统对手术视野的可视质量进行分级。

结果

所有组在手术开始后 60 分钟时的 MBP 和平均 HR 相似。三组之间的手术分级评分无显著差异(P = 0.83)。

结论

在这项对三种麻醉组合(PRO/REM、SEV/REM 和 DES/REM)的比较研究中,我们观察到在接受控制性血压和心率的 ESS 患者中,手术分级评分没有显著差异。

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