Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.
Muscle Nerve. 2011 Feb;43(2):286-8. doi: 10.1002/mus.21865.
We report a 53-year-old woman with an unusual presentation characterized by acute onset of generalized sensory symptoms associated with anhidrosis, anosmia, ageusia, and elevated titers of anti-GalNAc-GD1a antibodies. After intravenous immunoglobulin therapy, a remarkable improvement in the pain and temperature sensation was noted in her face, trunk, and extremities. The impaired pain and temperature sensation remained distributed along cranial and spinal dermatomes in a non-length-dependent manner, suggesting that the ganglionopathy affected small neurons.
我们报告了一例 53 岁女性，其表现不典型，特征为急性发作的全身性感觉症状，伴有无汗、嗅觉丧失、味觉丧失和抗 GalNAc-GD1a 抗体滴度升高。静脉注射免疫球蛋白治疗后，她面部、躯干和四肢的疼痛和温度感觉显著改善。受损的疼痛和温度感觉仍然以非长度依赖性方式沿着颅神经和脊神经皮节分布，表明神经节病变影响小神经元。
