Lukshina A A, Urakov S V, Loshakov V A
Zh Vopr Neirokhir Im N N Burdenko. 2010 Jul-Sep(3):25-31; discussion 31.
The rate of temporal lobe gliomas among all hemispheric glial tumors is up to 30%. Psychiatric disorders are typical for temporal lesions and could be even single manifestation of the disease. There is a rich variety of different psychopathologic and epileptic signs exactly in cases of temporal gliomas in comparison to tumors of other localizations. In our study we investigated psychiatric disorders on statistically significant group of patients (140 cases) with temporal lobe tumors with considerations of side, localization, histology of lesion and functional asymmetry of patients. We revealed psychiatric disorders in 72% of patients, mainly in glioblastoma. Seizures were more typical for WHO Grade I and II gliomas. Psychopathologic symptoms were more typical for left side lesions. Lefthanders had psychiatric disorders significantly more frequently than righthanders (p < 0.05). After surgical removal of tumor the rate of psychiatric disorders didn't differ statistically (p < 0.05) by 2 years follow-up. Complete regress of seizures was observe in 56% of cases.
在所有半球性胶质瘤中，颞叶胶质瘤的发生率高达30%。精神障碍是颞叶病变的典型表现，甚至可能是该疾病的唯一表现。与其他部位的肿瘤相比，颞叶胶质瘤患者确实存在丰富多样的不同精神病理和癫痫症状。在我们的研究中，我们对一组具有统计学意义的颞叶肿瘤患者（140例）进行了精神障碍调查，考虑了病变的侧别、部位、组织学以及患者的功能不对称性。我们发现72%的患者存在精神障碍，主要见于胶质母细胞瘤。癫痫发作在WHO I级和II级胶质瘤中更为典型。精神病理症状在左侧病变中更为典型。左利手患者患精神障碍的频率明显高于右利手患者（p<0.05）。肿瘤手术切除后，经过2年随访，精神障碍发生率在统计学上无差异（p<0.05）。56%的病例癫痫发作完全缓解。
