Division of Urology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada.
J Urol. 2011 Mar;185(3):1077-82. doi: 10.1016/j.juro.2010.10.047. Epub 2011 Jan 21.
Although staged buccal mucosa graft urethroplasty is a well accepted technique for salvage urethroplasty, there are few reports on this procedure for redo hypospadias repair in children.
We reviewed patients who underwent staged buccal mucosa graft urethroplasty for redo hypospadias repair. Age, quality of graft before tubularization, meatal position, presence of balanitis xerotica obliterans and complications were recorded.
A total of 30 patients underwent 32 repairs during a 5-year period. Mean age at first stage was 7 years (range 1 to 17) and mean interval between stages was 9.3 months (5 to 13). Mean followup after second stage was 25 months (range 10 to 46). Meatal position before first stage was proximal in 44% of patients, mid shaft in 39% and distal in 16%. Nine patients had biopsy proved balanitis xerotica obliterans. There were no donor site complications. Four patients underwent a redo grafting procedure. Complications after second stage occurred in 11 of 32 repairs (34%), consisting of urethral stenosis in 5, glanular dehiscence in 3 and urethrocutaneous fistula in 3. A third of the patients had some degree of graft fibrosis/induration after the first stage. These patients were prone to more complications at second stage (9 of 11, 82%), compared to patients without these unfavorable findings (4 of 21, 19%; p<0.001). Presence of balanitis xerotica obliterans and meatal position were not significant factors associated with adverse outcomes.
Staged buccal mucosa graft urethroplasty is a suitable technique for salvage urethroplasty. Complications after second stage were seen in approximately a third of patients, mainly those with fibrotic/indurated grafts.
尽管分期颊黏膜移植尿道成形术是一种被广泛接受的挽救性尿道成形术方法,但关于该方法在儿童尿道下裂修复中的应用却鲜有报道。
我们回顾了接受分期颊黏膜移植尿道成形术修复尿道下裂的患者。记录了患者的年龄、管状化前移植物的质量、尿道口位置、是否存在干燥性龟头炎和并发症。
在 5 年期间,共有 30 名患者接受了 32 次修复。第一期手术的平均年龄为 7 岁(范围 1 至 17 岁),两期手术的平均间隔为 9.3 个月(5 至 13 个月)。第二期手术后的平均随访时间为 25 个月(范围 10 至 46 个月)。第一期手术前尿道口位置近端占 44%,中段占 39%,远端占 16%。9 名患者经活检证实为干燥性龟头炎。供区无并发症。4 名患者行再次移植物修复术。第二期手术后发生并发症 11 例(34%),包括尿道狭窄 5 例、龟头裂开 3 例和尿道皮肤瘘 3 例。第一期手术后,有三分之一的患者移植物有不同程度的纤维化/硬结。与无这些不良发现的患者(4 例,19%)相比,这些患者第二期手术后更容易发生并发症(9 例,82%)(p<0.001)。干燥性龟头炎和尿道口位置不是与不良结局相关的显著因素。
分期颊黏膜移植尿道成形术是一种适合的挽救性尿道成形术技术。第二期手术后约有三分之一的患者出现并发症,主要是那些移植物纤维化/硬结的患者。