• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

尿道下裂修复术遗留问题的长期后果。

The long-term consequences of the hypospadias salvage repair issue.

机构信息

Pediatric Urology Division, Urology Department, Assiut University, Assiut, Egypt.

出版信息

BMC Pediatr. 2024 Jan 19;24(1):58. doi: 10.1186/s12887-024-04534-3.

DOI:10.1186/s12887-024-04534-3
PMID:38243172
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10797878/
Abstract

PURPOSE

To present the long-term results of redo-hypospadias at our tertiary referral center following a failed prior repair.

METHODS

One hundred sixty-four individuals with a history of unsuccessful repairs qualified for our retrospective cohort study. Our inclusion criteria were as follows: pre-operative data that was accessible, redo-hypospadias that was successfully repaired, and at least three years of follow-up at the last hospital visit.

RESULTS

The mean patient age was 91.3 ± 21.1 months. The mean follow-up after successful repair was 41.3 ± 3.1 months. Ninety-two (group A) had one prior repair, and 72 (group B) had 2 or 3 repairs. Group A underwent six primary techniques: 32 underwent Onlay Island Flap (OIF), 10 underwent Mathieu, 12 underwent Tubularized Incised Plate Urethroplasty (TIPU), 8 underwent Urethral Mobilization (UM), and 34 underwent Buccal Mucosal Graft (BMG) { dorsal inlay Graft Urethroplasty (DIGU) in 4 and staged BMG in 30 patients}. In group B, four procedures were used: TIPU in 4, UM in 6, and BMG in 62 (staged BMG in 50 cases and DIGU in 12).

CONCLUSIONS

The selected type of repair will depend on many factors, like residual healthy local skin and expertise. Safe techniques for repair of redo hypospadias after its 1st failure include TIPU, Mathieu, UM, OIF, and DIGU for distal varieties. After 2nd or 3rd repair DIGU, UM, and TIPU can be performed in distal types, while staged BMG can be applied for proximal ones.

摘要

目的

在我们的三级转诊中心，报告在初次修复失败后再次修复的尿道下裂的长期结果。

方法

共有 164 名曾接受过不成功修复的个体符合我们的回顾性队列研究标准。我们的纳入标准如下：可获得术前数据、再次修复成功的尿道下裂和最后一次就诊时至少 3 年的随访。

结果

患者平均年龄为 91.3±21.1 个月。成功修复后的平均随访时间为 41.3±3.1 个月。92 例（A 组）接受过一次初次修复，72 例（B 组）接受过 2 次或 3 次修复。A 组接受了 6 种主要技术：32 例行 Onlay Island Flap（OIF），10 例行 Mathieu，12 例行 Tubularized Incised Plate Urethroplasty（TIPU），8 例行 Urethral Mobilization（UM），34 例行 Buccal Mucosal Graft（BMG）{4 例行 dorsal inlay Graft Urethroplasty（DIGU）和 30 例行 staged BMG}。B 组中，4 例行 TIPU，6 例行 UM，62 例行 BMG（50 例行 staged BMG 和 12 例行 DIGU）。

结论

修复类型的选择将取决于许多因素，如残留的健康局部皮肤和专业知识。初次失败后再次修复尿道下裂的安全技术包括 TIPU、Mathieu、UM、OIF 和 DIGU 用于远端类型。在第 2 次或第 3 次修复时，DIGU、UM 和 TIPU 可用于远端类型，而 staged BMG 可用于近端类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/5cf38a7f3052/12887_2024_4534_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/f76db016ab4e/12887_2024_4534_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/c79584513170/12887_2024_4534_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/aed552e12894/12887_2024_4534_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/6a38752b3a74/12887_2024_4534_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/5cf38a7f3052/12887_2024_4534_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/f76db016ab4e/12887_2024_4534_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/c79584513170/12887_2024_4534_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/aed552e12894/12887_2024_4534_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/6a38752b3a74/12887_2024_4534_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f62/10797878/5cf38a7f3052/12887_2024_4534_Fig5_HTML.jpg

相似文献

1
The long-term consequences of the hypospadias salvage repair issue.尿道下裂修复术遗留问题的长期后果。
BMC Pediatr. 2024 Jan 19;24(1):58. doi: 10.1186/s12887-024-04534-3.
2
Single-Stage Pedicle Preputial Tube Substitution Urethroplasty with Corpora Cavernosa Augmentation Using Buccal Mucosa Graft for Primary Peno-Scrotal Hypospadias Re-pair in Adults.单阶段带蒂包皮管替代尿道成形术联合阴茎海绵体增大术，采用颊黏膜移植治疗成人原发性阴茎阴囊型尿道下裂修复术
Int Braz J Urol. 2025 Jul-Aug;51(4). doi: 10.1590/S1677-5538.IBJU.2024.0650.
3
Are there any benefits of using an inlay graft in the treatment of primary hypospadias in children? A systematic review and metanalysis.在儿童原发性尿道下裂的治疗中，使用嵌片移植物有何益处？系统评价和荟萃分析。
J Pediatr Urol. 2021 Jun;17(3):303-315. doi: 10.1016/j.jpurol.2021.02.013. Epub 2021 Feb 19.
4
Surgical and functional outcomes of Dorsal Inlay Graft urethroplasty in revision vs primary hypospadias repair in the pediatric age.背侧镶嵌移植物尿道成形术在小儿年龄的原发性和复发性尿道下裂修复中的手术和功能结果。
J Pediatr Urol. 2024 Aug;20(4):646-652. doi: 10.1016/j.jpurol.2024.01.012. Epub 2024 Jan 13.
5
Comparative Study Between Autologous Platelet-rich Fibrin Membrane and Local Flaps as Intervening Layer in Management of Distal Hypospadias.富自体血小板纤维蛋白膜与局部皮瓣作为远端尿道下裂治疗干预层的比较研究
J Pediatr Surg. 2025 Jan;60(1):161994. doi: 10.1016/j.jpedsurg.2024.161994. Epub 2024 Oct 11.
6
Reducing fistula rate in hypospadias repair: A comparative study between standard tubularized incised plate repair and incorporation of a layer of spongiosum tissue.降低尿道下裂修复术后瘘管发生率：标准管状切开板修复与海绵体组织层合并的对比研究。
J Pediatr Urol. 2024 Aug;20(4):675-679. doi: 10.1016/j.jpurol.2024.04.004. Epub 2024 Apr 12.
7
Meta-analysis comparing the outcomes of single stage (foreskin pedicled tube) versus two stage (foreskin free graft & foreskin pedicled flap) repair for proximal hypospadias in the last decade.近十年一期（带蒂包皮管状皮瓣）与二期（游离皮片移植与带蒂包皮皮瓣）修复近端尿道下裂的结局比较的荟萃分析。
J Pediatr Urol. 2021 Oct;17(5):681-689. doi: 10.1016/j.jpurol.2021.05.014. Epub 2021 May 17.
8
Can paediatric surgical registrars safely perform supervised hypospadias surgery?儿科外科住院医师是否可以安全地进行监督下的尿道下裂手术？
J Pediatr Urol. 2024 Aug;20(4):659-666. doi: 10.1016/j.jpurol.2024.01.030. Epub 2024 Feb 8.
9
Outcomes in distal hypospadias: a systematic review of the Mathieu and tubularized incised plate repairs.远端型尿道下裂的治疗效果：Mathieu 术和管状切开皮瓣术的系统评价。
J Pediatr Urol. 2012 Jun;8(3):307-12. doi: 10.1016/j.jpurol.2010.11.008. Epub 2010 Dec 14.
10
Algorithm for Optimal Urethral Coverage in Hypospadias and Fistula Repair: A Systematic Review.尿道下裂和瘘管修复中尿道最佳覆盖算法：系统评价。
Eur Urol. 2016 Aug;70(2):293-8. doi: 10.1016/j.eururo.2015.12.047. Epub 2016 Jan 15.

本文引用的文献

1
The adolescent glans penis: Functional and aesthetic issues following childhood hypospadias repair.青少年龟头：儿童尿道下裂修复后的功能和美学问题。
J Pediatr Urol. 2021 Oct;17(5):609.e1-609.e8. doi: 10.1016/j.jpurol.2021.07.030. Epub 2021 Aug 13.
2
A Case Series of Penile Skin Grafting in Children.儿童阴茎皮肤移植病例系列
European J Pediatr Surg Rep. 2020 Jan;8(1):e77-e80. doi: 10.1055/s-0040-1716525. Epub 2020 Oct 21.
3
Ingrafts in hypospadias surgery: Longer-term outcomes.尿道下裂手术中的移植物：长期结果。
J Pediatr Urol. 2020 Oct;16(5):555.e1-555.e5. doi: 10.1016/j.jpurol.2020.04.030. Epub 2020 May 7.
4
Role of uroflowmetry before and after hypospadias repair.尿道下裂修复前后尿流率测定的作用
Urol Ann. 2018 Jan-Mar;10(1):52-58. doi: 10.4103/UA.UA_78_17.
5
Resurfacing the Penis of Complex Hypospadias Repair ("Hypospadias Cripples").阴茎复杂型尿道下裂修复术（“尿道下裂残障”）的再造。
J Urol. 2017 Mar;197(3 Pt 2):859-864. doi: 10.1016/j.juro.2016.09.075. Epub 2017 Jan 26.
6
Preliminary experience using a tunica vaginalis flap as the dorsal component of Bracka's urethroplasty.使用睾丸鞘膜瓣作为布拉克尿道成形术背侧成分的初步经验。
BJU Int. 2017 Mar;119(3):470-473. doi: 10.1111/bju.13604. Epub 2016 Aug 17.
7
Glans size is an independent risk factor for urethroplasty complications after hypospadias repair.龟头大小是尿道下裂修复术后尿道成形术并发症的独立危险因素。
J Pediatr Urol. 2015 Dec;11(6):355.e1-5. doi: 10.1016/j.jpurol.2015.05.029. Epub 2015 Aug 13.
8
Failed hypospadias in paediatric patients.小儿患者的尿道下裂失败案例。
Nat Rev Urol. 2013 Nov;10(11):657-66. doi: 10.1038/nrurol.2013.164. Epub 2013 Aug 6.
9
Which type of urethroplasty in failed hypospadias repair? An 8-year follow up.哪种类型的尿道成形术适用于失败的尿道下裂修复？8 年随访。
J Pediatr Urol. 2013 Dec;9(6 Pt B):1150-4. doi: 10.1016/j.jpurol.2013.04.015. Epub 2013 May 30.
10
Importance of urinary flow studies after hypospadias repair: a systematic review.尿道下裂修复后尿流研究的重要性：系统评价。
Int J Urol. 2011 Nov;18(11):757-61. doi: 10.1111/j.1442-2042.2011.02839.x. Epub 2011 Aug 30.