United BioSource Corporation, Center for Health Outcomes Research, Bethesda, MD 20814, USA.
Urology. 2011 May;77(5):1081-7. doi: 10.1016/j.urology.2010.08.039. Epub 2011 Jan 22.
To estimate the prevalence of and bother associated with overactive bladder (OAB) in adults aged ≥40 years in the United States, using current International Continence Society definitions.
Internet-based panel members were selected randomly to participate in EpiLUTS, a cross-sectional, population-representative survey. Participants used Likert scales to rate how often they experienced individual lower urinary tract symptoms during the previous 4 weeks and how much bother they experienced. Based on responses to questions regarding urgency and urgency urinary incontinence, OAB symptoms were categorized as occurring at least "sometimes" or at least "often." Symptom bother was categorized as at least "somewhat" or at least "quite a bit."
The response rate was 59.6%, with a final sample of 9416 men and 10,584 women. Prevalence of OAB symptoms at least "sometimes" was 27.2% and 43.1% for men and women, respectively; prevalence of OAB at least "often" was 15.8% and 32.6%, respectively. Among men with OAB symptoms at least "sometimes," 60.0% were bothered at least "somewhat" and 27.8% were bothered at least "quite a bit." Among women, bother rates were 67.6% and 38.9%, respectively. Among respondents with OAB at least "often," 67.8% and 38.2% of men and 73.0% and 47.1% of women reported being bothered at least "somewhat" and at least "quite a bit," respectively. We estimate that 29.8 million adults aged ≥40 years in the United States have bothersome OAB symptoms.
Bothersome OAB symptoms are highly prevalent among men and women aged ≥40 years in the United States.
使用国际尿控协会（ICS）的现行定义，估计美国≥40 岁成年人中膀胱过度活动症（OAB）的患病率及其相关困扰。
随机选择互联网面板成员参与 EpiLUTS，这是一项横断面、具有代表性的人群调查。参与者使用李克特量表评估他们在过去 4 周内经历个体下尿路症状的频率以及经历的困扰程度。根据有关尿急和急迫性尿失禁问题的回答，将 OAB 症状分为至少“有时”或至少“经常”发生。症状困扰程度分为至少“有些”或至少“相当多”。
响应率为 59.6%，最终样本包括 9416 名男性和 10584 名女性。男性和女性至少“有时”出现 OAB 症状的患病率分别为 27.2%和 43.1%；至少“经常”出现 OAB 的患病率分别为 15.8%和 32.6%。在至少“有时”出现 OAB 症状的男性中，60.0%的人感到至少“有些”困扰，27.8%的人感到至少“相当多”困扰。在女性中，困扰率分别为 67.6%和 38.9%。在至少“经常”出现 OAB 的受访者中，67.8%和 38.2%的男性以及 73.0%和 47.1%的女性分别报告感到至少“有些”和至少“相当多”困扰。我们估计，美国≥40 岁的 2980 万成年人有令人困扰的 OAB 症状。
美国≥40 岁的男性和女性中，有令人困扰的 OAB 症状的比例非常高。
