Department of Urology, UCSF Children's Hospital, San Francisco, California 94143-0738, USA.
Urology. 2011 Jun;77(6):1455-9. doi: 10.1016/j.urology.2010.10.008. Epub 2011 Jan 22.
To report the breadth of ovarian conditions that pediatric urologists may encounter through diverse referral patterns.
Two regional pediatric centers reviewed cases from 2000 to 2010, yielding 13 females with gonad-related conditions.
Six of 13 patients (46%) were referred for a presumed urological condition that was later discovered to be of ovarian origin or were already known to the urology clinic for a congenital urological anomaly. Six patients had tumor markers drawn, all of which were normal. Median age was 11.2 years. The most common presenting symptoms were pain (6/13), emesis (5/13), and precocious puberty (2/13). Median mass diameter was 7.5 cm with 2 patients having masses greater than 20 cm. Histologic diagnosis was mature teratoma (4/13), streak gonad (3/13), and hemorrhagic cyst (2/13). Two patients had potentially malignant tumors (immature teratoma and juvenile granulosa cell tumor).
At our centers, an ovarian condition is encountered an average of 1.3 times per year. As management of pediatric ovarian cysts and masses is controversial, pediatric urologists should be familiar with the diagnosis and treatment of such conditions.
报告小儿泌尿科医生可能通过不同的转诊模式遇到的各种卵巢疾病。
两个地区性儿科中心回顾了 2000 年至 2010 年的病例,共发现 13 名与性腺相关的女性患者。
13 名患者中有 6 名(46%)因假定的泌尿科疾病转诊,但后来发现该疾病源于卵巢,或因先天性泌尿科异常已在泌尿科诊所就诊。6 名患者抽取了肿瘤标志物,均正常。中位年龄为 11.2 岁。最常见的症状是疼痛(6/13)、呕吐(5/13)和性早熟(2/13)。中位肿块直径为 7.5cm,有 2 名患者的肿块大于 20cm。组织学诊断为成熟畸胎瘤(4/13)、条纹性腺(3/13)和出血性囊肿(2/13)。有 2 名患者患有潜在恶性肿瘤(不成熟畸胎瘤和幼年颗粒细胞瘤)。
在我们的中心,平均每年会遇到 1.3 例卵巢疾病。由于小儿卵巢囊肿和肿块的治疗存在争议,小儿泌尿科医生应熟悉此类疾病的诊断和治疗。