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Nuclear receptor COUP-TFII controls pancreatic islet tumor angiogenesis by regulating vascular endothelial growth factor/vascular endothelial growth factor receptor-2 signaling.
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Generation of ES cells for conditional expression of nuclear receptors and coregulators in vivo.
Mol Endocrinol. 2010 Jun;24(6):1297-304. doi: 10.1210/me.2010-0068. Epub 2010 Apr 9.
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Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development.
J Clin Invest. 2010 May;120(5):1694-707. doi: 10.1172/JCI40101. Epub 2010 Apr 1.
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The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells.
Genes Dev. 2010 Apr 1;24(7):696-707. doi: 10.1101/gad.1859310.
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Specification of arterial, venous, and lymphatic endothelial cells during embryonic development.
Histol Histopathol. 2010 May;25(5):637-46. doi: 10.14670/HH-25.637.
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Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization.
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COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis.
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The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors.
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