Markovic Sergije, Zigic Zlata, Ramic Suada, Hadzihalilovic Jasminka
Department of Histology and Embryology, School of Medicine, School of Natural Sciences; University of Tuzla, Tuzla, Bosnia and Herzegovina.
Med Glas (Zenica). 2010 Aug;7(2):160-5.
To determine quantitative parameters of volume density and absolute volume of syncytiotrophoblast in resorption villi of control and experimental group, compare the results and search for correlation between structural parameters of resorption villi and pregnancy age.
The research was performed on 60 human placentas of term pregnancy: 30 placentas of pregnant women of age 20 - 34 (control group), and 30 placentas of pregnant women of age 35 and older (experimental group). Stereological analysis was performed on multipurpose testing system M42 with 40 times objective magnification.
Average volume density of syncytiotrophoblast in resorption villi of experimental and control group was Vvss = (0,489 ± 0,032) mm0 and Vvsm = (0,389 ± 0,078) mm0 , respectively. Statistical analysis of results using Student t-test indicated a significantly higher volume density of syncytiotrophoblast of resorption villi in the experimental than in the control group (p < 0,001). Absolute volume of syncytiotrophoblast in resorption villi of the experimental and control groups was Vss = (205,250±40,894) cm3 and Vsm = (178,386 ± 44,413) cm3, respectively. We have found a significantly higher absolute volume of syncytiotrophoblast in resorption villi in the experimental than in the control group (p < 0,005).
Statistically significant higher values of volume density and absolute volume of syncytiotrophoblast in resorption villi of placentas in older pregnant women represent a compensatory mechanism as a response to decreased metabolic exchange between a mother and a fetus.
确定对照组和实验组吸收绒毛中合体滋养层的体积密度和绝对体积的定量参数，比较结果并寻找吸收绒毛结构参数与妊娠年龄之间的相关性。
对60例足月妊娠的人胎盘进行研究：20 - 34岁孕妇的30个胎盘（对照组），以及35岁及以上孕妇的30个胎盘（实验组）。在具有40倍物镜放大倍数的多功能测试系统M42上进行体视学分析。
实验组和对照组吸收绒毛中合体滋养层的平均体积密度分别为Vvss =（0.489±0.032）mm³和Vvsm =（0.389±0.078）mm³。使用学生t检验对结果进行统计分析表明，实验组吸收绒毛中合体滋养层的体积密度显著高于对照组（p <0.001）。实验组和对照组吸收绒毛中合体滋养层的绝对体积分别为Vss =（205.250±40.894）cm³和Vsm =（178.386±44.413）cm³。我们发现实验组吸收绒毛中合体滋养层的绝对体积显著高于对照组（p <0.005）。
老年孕妇胎盘中吸收绒毛中合体滋养层的体积密度和绝对体积在统计学上显著更高的值代表了一种补偿机制，作为对母婴之间代谢交换减少的反应。
