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[生物膜与人工关节感染关系的研究进展]

[Progress of relationship between biofilm and prosthetic joint infection].

作者信息

Mao Yanjie, Shen Hao, Jiang Yao

机构信息

Department of Orthopaedics, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, PR China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2010 Dec;24(12):1463-8.

Abstract

OBJECTIVE

To summarize the effect of biofilm (BF) on the occurrence of prosthetic joint infection (PJI).

METHODS

The domestic and abroad original literature in recent years about the relationship between BF and PJI was reviewed.

RESULTS

Infection is a critical complication for prosthetic joint replacement. Basic research shows one of the reasons for PJI is BF. After adherence of the bacteria to the surface of prosthetic joint, BF forms through a series of regulation and control system. And it lead to the occurrence of PJI. Recently a lot of progress have been made in the research fields of BF related PJI, which have covered aetiology, diagnosis, treatment, and prevention. Different studies show that BF has close relationship with PJI.

CONCLUSION

BF is proved to have close relationship with PJI. It is important on clinical significances to diagnose, treat, and prevent PJI.

摘要

目的

总结生物膜(BF)对人工关节感染(PJI)发生的影响。

方法

回顾近年来国内外关于BF与PJI关系的原始文献。

结果

感染是人工关节置换的关键并发症。基础研究表明PJI的原因之一是BF。细菌粘附到人工关节表面后,BF通过一系列调控系统形成。并导致PJI的发生。近年来,BF相关PJI的研究领域取得了很多进展,涵盖了病因学、诊断、治疗和预防。不同研究表明BF与PJI密切相关。

结论

已证明BF与PJI密切相关。对PJI进行诊断、治疗和预防具有重要的临床意义。

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