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Obesity in 2010: the future of obesity medicine: where do we go from here?

作者信息

Wright Suzanne M, Aronne Louis J

机构信息

Comprehensive Weight Control Program, Weill Cornell Medical College, 1165 York Avenue, New York, NY 10065, USA.

出版信息

Nat Rev Endocrinol. 2011 Feb;7(2):69-70. doi: 10.1038/nrendo.2010.231.

DOI:10.1038/nrendo.2010.231
PMID:21263435
Abstract
摘要

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Obesity in 2010: the future of obesity medicine: where do we go from here?2010年的肥胖问题:肥胖医学的未来:我们从这里走向何方?
Nat Rev Endocrinol. 2011 Feb;7(2):69-70. doi: 10.1038/nrendo.2010.231.
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4
Companies throw their weight behind new antiobesity drugs.各大公司纷纷大力支持新型抗肥胖药物。
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The pharmacologic management of obesity.肥胖的药物治疗
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Endocrinol Nutr. 2014 Dec;61(10):501-4. doi: 10.1016/j.endonu.2014.11.002.
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8
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本文引用的文献

1
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects.西布曲明对超重和肥胖受试者心血管结局的影响。
N Engl J Med. 2010 Sep 2;363(10):905-17. doi: 10.1056/NEJMoa1003114.
2
Phentermine, topiramate and their combination for the treatment of adiposopathy ('sick fat') and metabolic disease.苯丁胺、托吡酯及其联合用药治疗脂肪代谢障碍(“病态肥胖”)和代谢性疾病。
Expert Rev Cardiovasc Ther. 2010 Dec;8(12):1777-801. doi: 10.1586/erc.10.125. Epub 2010 Aug 16.
3
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial.
乳酸杆菌通过肠道从宿主中清除游离脂肪酸以治疗肥胖症。
FEBS Open Bio. 2016 Jan 18;6(1):64-76. doi: 10.1002/2211-5463.12024. eCollection 2016 Jan.
4
Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.前蛋白转化酶枯草溶菌素1(PCSK1)常见非同义变异对体重指数变化及肥胖风险的贡献:一项基于多达331175例个体证据的系统评价和荟萃分析
Hum Mol Genet. 2015 Jun 15;24(12):3582-94. doi: 10.1093/hmg/ddv097. Epub 2015 Mar 17.
5
Evaluation of AMG 076, a potent and selective MCHR1 antagonist, in rodent and primate obesity models.评估 AMG 076,一种强效和选择性的 MCHR1 拮抗剂,在啮齿动物和灵长类动物肥胖模型中的作用。
Pharmacol Res Perspect. 2013 Oct;1(1):e00003. doi: 10.1002/prp2.3. Epub 2013 Sep 17.
6
Myths, presumptions, and facts about obesity.肥胖的误区、假设和事实。
N Engl J Med. 2013 Jan 31;368(5):446-54. doi: 10.1056/NEJMsa1208051.
7
Design, synthesis, structural and functional characterization of novel melanocortin agonists based on the cyclotide kalata B1.基于环肽kalata B1 的新型促黑激素激动剂的设计、合成、结构和功能表征。
J Biol Chem. 2012 Nov 23;287(48):40493-501. doi: 10.1074/jbc.M112.395442. Epub 2012 Sep 25.
8
Potential use of exenatide for the treatment of obesity.艾塞那肽在肥胖治疗中的潜在应用。
Expert Opin Investig Drugs. 2011 Dec;20(12):1717-22. doi: 10.1517/13543784.2011.630660. Epub 2011 Oct 24.
纳曲酮联合安非他酮对超重和肥胖成年人体重减轻的影响(COR-I):一项多中心、随机、双盲、安慰剂对照、3 期临床试验。
Lancet. 2010 Aug 21;376(9741):595-605. doi: 10.1016/S0140-6736(10)60888-4. Epub 2010 Jul 29.
4
Multicenter, placebo-controlled trial of lorcaserin for weight management.多中心、安慰剂对照的氯卡色林用于体重管理的试验。
N Engl J Med. 2010 Jul 15;363(3):245-56. doi: 10.1056/NEJMoa0909809.
5
Sibutramine in cardiovascular disease: is SCOUT the new STORM on the horizon?西布曲明与心血管疾病:SCOUT研究是否会成为即将到来的新“风暴”?
Eur Heart J. 2007 Dec;28(23):2830-1. doi: 10.1093/eurheartj/ehm493. Epub 2007 Nov 5.
6
Anorectics on trial: a half century of federal regulation of prescription appetite suppressants.接受试验的食欲抑制剂:联邦对处方类食欲抑制剂监管的半个世纪
Ann Intern Med. 2005 Sep 6;143(5):380-5. doi: 10.7326/0003-4819-143-5-200509060-00013.