Animal Genetics Division, National Bureau of Animal Genetic Resources, Karnal, Haryana, India.
Biochem Genet. 2011 Aug;49(7-8):449-57. doi: 10.1007/s10528-011-9421-0. Epub 2011 Jan 25.
This study illustrates the genetic diversity and relationships within and among six Indian sheep breeds of the northwestern arid region of Rajasthan, based on microsatellite markers. The range of allele diversity was 7.72-9.56, and gene diversity was 0.686-0.766, revealing that these breeds possessed substantial amounts of genetic diversity. Positive F (IS) values suggested a deficit of heterozygotes in all six breeds. Despite the declining status of the Marwari, Chokla, Jaisalmeri, Magra and Pugal breeds, an absence of a recent genetic bottleneck was evident from the data. The genetic differentiation estimate (F (ST) = 6.1%) suggested low levels of differentiation between the breeds. Genetic distance estimates revealed a close relationship between the Magra-Pugal and Nali-Jaisalmeri breed pairs. This information forms a framework for designing genetic management and conservation programs for these valuable ovine breeds.
本研究利用微卫星标记，阐明了印度西北部干旱地区的 6 个绵羊品种的遗传多样性和品种内及品种间的关系。等位基因多样性范围为 7.72-9.56，基因多样性为 0.686-0.766，表明这些品种具有丰富的遗传多样性。所有 6 个品种的正 F（IS）值表明杂合子缺失。尽管 Marwari、Chokla、Jaisalmeri、Magra 和 Pugal 品种的数量在减少，但数据显示，这些品种并未经历近期的遗传瓶颈。遗传分化估计值（F（ST）= 6.1%）表明品种间的分化程度较低。遗传距离估计揭示了 Magra-Pugal 和 Nali-Jaisalmeri 品种对之间的密切关系。这些信息为这些有价值的绵羊品种的遗传管理和保护计划提供了框架。
