对于结直肠癌肝转移，应提供何种、如何以及何时进行非手术治疗。 - Suppr

What, how, and when to offer nonresectional therapy for colorectal cancer liver metastases.

作者信息

Boutros Cherif, Espat N Joseph

机构信息

Hepatobiliary and Surgical Oncology, Roger Williams Medical Center, 825 Chalkstone Ave., Prior 4, Providence, RI 02908, USA.

出版信息

J Gastrointest Surg. 2011 Mar;15(3):420-2. doi: 10.1007/s11605-011-1428-7. Epub 2011 Jan 25.

DOI:10.1007/s11605-011-1428-7

PMID:21264686

Abstract

摘要

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What, how, and when to offer nonresectional therapy for colorectal cancer liver metastases.对于结直肠癌肝转移，应提供何种、如何以及何时进行非手术治疗。

J Gastrointest Surg. 2011 Mar;15(3):420-2. doi: 10.1007/s11605-011-1428-7. Epub 2011 Jan 25.

Nonresectional regional therapies for metastatic colorectal cancer to the liver.转移性结直肠癌肝转移的非切除区域治疗

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Liver-directed therapies: does it make sense in the current therapeutic strategy for patients with confined liver colorectal metastases?肝脏导向治疗：对于局限于肝脏的结直肠癌转移患者，目前的治疗策略是否合理？

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The role of radioembolization in colorectal cancer treatment.放射性栓塞在结直肠癌治疗中的作用。

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Locoregional Liver-Directed Therapies to Treat Unresectable Colorectal Liver Metastases: A Review.局部区域肝脏导向治疗不可切除结直肠癌肝转移：综述。

Oncology (Williston Park). 2022 Feb 8;36(2):108-114. doi: 10.46883/2022.25920945.

Evidence-Based Integration of Yttrium-90 Radioembolization in the Contemporary Management of Hepatic Metastases from Colorectal Cancer.基于证据的钇-90放射性栓塞在当代结直肠癌肝转移管理中的整合应用

Tech Vasc Interv Radiol. 2019 Jun;22(2):74-80. doi: 10.1053/j.tvir.2019.02.007. Epub 2019 Feb 27.

Liver metastases from colorectal cancer: radioembolization with systemic therapy.结直肠癌肝转移：联合全身治疗的放射性栓塞治疗。

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Locoregional therapies for metastatic colorectal carcinoma to the liver--an evidence-based review.转移性结直肠癌肝转移的局部区域治疗——循证综述。

J Surg Oncol. 2014 Aug;110(2):182-96. doi: 10.1002/jso.23619. Epub 2014 Apr 24.

Yttrium-90 radioembolization for the treatment of chemorefractory colorectal liver metastases: Technical results, clinical outcome and factors potentially influencing survival.钇-90放射性栓塞治疗化疗难治性结直肠癌肝转移：技术结果、临床结局及可能影响生存的因素

Acta Oncol. 2016;55(4):486-95. doi: 10.3109/0284186X.2015.1101151. Epub 2015 Dec 1.

Radioembolization of liver metastases from colorectal cancer using yttrium-90 microspheres with concomitant systemic oxaliplatin, fluorouracil, and leucovorin chemotherapy.使用钇-90微球对结直肠癌肝转移灶进行放射性栓塞，并同时进行奥沙利铂、氟尿嘧啶和亚叶酸钙全身化疗。

J Clin Oncol. 2007 Mar 20;25(9):1099-106. doi: 10.1200/JCO.2006.08.7916.

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Rep Pract Oncol Radiother. 2017 Mar-Apr;22(2):103-110. doi: 10.1016/j.rpor.2017.02.006. Epub 2017 Apr 6.

Integrating respiratory-gated PET-based target volume delineation in liver SBRT planning, a pilot study.肝脏立体定向放疗计划中整合基于呼吸门控PET的靶区勾画：一项初步研究

Radiat Oncol. 2014 Jun 2;9:127. doi: 10.1186/1748-717X-9-127.

Thermal tumor ablation therapy for colorectal cancer hepatic metastasis.结直肠癌肝转移的热肿瘤消融治疗。

J Gastrointest Oncol. 2012 Mar;3(1):69-77. doi: 10.3978/j.issn.2078-6891.2012.008.

SSAT/AHPBA Joint Symposium: Today's approaches to colorectal cancer (CRC) liver metastases.SSAT/AHPBA联合研讨会：当今结直肠癌（CRC）肝转移的治疗方法

J Gastrointest Surg. 2011 Mar;15(3):404-5. doi: 10.1007/s11605-011-1425-x. Epub 2011 Feb 1.

本文引用的文献

Surgical downstaging and neo-adjuvant therapy in metastatic colorectal carcinoma with irinotecan drug-eluting beads: a multi-institutional study.伊立替康载药微球在转移性结直肠癌中的手术降期和新辅助治疗：一项多机构研究。

HPB (Oxford). 2010 Feb;12(1):31-6. doi: 10.1111/j.1477-2574.2009.00117.x.

Five-year survival following radiofrequency ablation of small, solitary, hepatic colorectal metastases.小的、孤立性肝结直肠癌转移灶射频消融后的5年生存率

J Vasc Interv Radiol. 2008 May;19(5):712-7. doi: 10.1016/j.jvir.2008.01.016. Epub 2008 Mar 17.

Radiofrequency ablation of primary and metastatic liver tumors: a critical review of the literature.原发性和转移性肝肿瘤的射频消融：文献综述

Am J Surg. 2008 Apr;195(4):508-20. doi: 10.1016/j.amjsurg.2007.06.024.

Hepatic tumor ablation with clustered microwave antennae: the US Phase II trial.簇状微波天线肝肿瘤消融术：美国 II 期试验。

HPB (Oxford). 2007;9(2):120-4. doi: 10.1080/13651820701222677.

Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer.钇90微球联合氟尿嘧啶/亚叶酸钙化疗与单纯氟尿嘧啶/亚叶酸钙化疗治疗晚期结直肠癌的随机2期试验

J Surg Oncol. 2004 Nov 1;88(2):78-85. doi: 10.1002/jso.20141.

Randomised trial of SIR-Spheres plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer.钇90微球联合化疗与单纯化疗治疗原发性大肠癌肝转移患者的随机试验

Ann Oncol. 2001 Dec;12(12):1711-20. doi: 10.1023/a:1013569329846.

Intrahepatic or systemic infusion of fluorodeoxyuridine in patients with liver metastases from colorectal carcinoma. A randomized trial.氟脱氧尿苷肝内或全身输注用于结直肠癌肝转移患者。一项随机试验。

Ann Intern Med. 1987 Oct;107(4):459-65. doi: 10.7326/0003-4819-107-4-459.

A randomized trial of continuous intravenous versus hepatic intraarterial floxuridine in patients with colorectal cancer metastatic to the liver: the Northern California Oncology Group trial.一项关于持续静脉注射氟尿苷与肝动脉注射氟尿苷治疗肝转移结直肠癌患者的随机试验：北加利福尼亚肿瘤学组试验

J Clin Oncol. 1989 Nov;7(11):1646-54. doi: 10.1200/JCO.1989.7.11.1646.

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What, how, and when to offer nonresectional therapy for colorectal cancer liver metastases.

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