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手术放大镜放大倍数可降低甲状腺全切除术后的低钙血症发生率。

Loupe magnification reduces postoperative hypocalcemia after total thyroidectomy.

作者信息

Pata Giacomo, Casella Claudio, Mittempergher Francesco, Cirillo Laura, Salerni Bruno

机构信息

Department of Medical & Surgical Sciences, 1st Division of General Surgery, University of Brescia, Brescia, Italy.

出版信息

Am Surg. 2010 Dec;76(12):1345-50.

Abstract

We aimed to evaluate the impact of loupe magnification (LM) on incidental parathyroid gland removal (from pathology reports), hypocalcemia, and recurrent laryngeal nerve (RLN) injury after total thyroidectomy and answer the question of whether this tool should be always recommended for patient's safety. Between January 2005 and December 2008, 126 patients underwent total thyroidectomy with routine use of 2.5 x galilean loupes; their charts were compared with data on 118 patients operated on between January 1997 and December 2000 without LM (two different equally skilled surgical teams operating in the two periods). LM decreased the rate of inadvertent parathyroid glands removal (3.8 vs 7.8% of total parathyroid glands; P = 0.01), as well as of biochemical (20.6 vs 33.9%; P = 0.028) and clinical (12.7 vs 33%; P = 0.0003) hypocalcemia after thyroidectomy. All cases (16 of 16) of symptomatic hypocalcaemia in the LM group proved to be associated with parathyroidectomy vs 76.9 per cent (30 of 39) without LM (P = 0.046). A trend toward decreased RLN injury rate, although statistically insignificant, was reported, being unilateral transient, unilateral permanent, and bilateral transient palsy rates 6.8, 2.5, and 1.7 per cent, respectively, without LM vs 4.8, 2.4, and 0.8 per cent, respectively, with LM (P = 0.69; P = 1, and P = 0.61, respectively). Our results do support the routine use of LM during total thyroidectomy.

摘要

我们旨在评估放大镜放大倍数(LM)对全甲状腺切除术后意外甲状旁腺切除(根据病理报告)、低钙血症和喉返神经(RLN)损伤的影响,并回答是否应始终推荐使用该工具以保障患者安全的问题。2005年1月至2008年12月期间,126例患者接受了全甲状腺切除术,并常规使用2.5倍伽利略放大镜;将他们的病历与1997年1月至2000年12月期间接受手术的118例未使用LM的患者的数据进行比较(两个时期由两个同样技术娴熟的不同手术团队操作)。LM降低了意外甲状旁腺切除率(占总甲状旁腺的3.8%对7.8%;P = 0.01),以及甲状腺切除术后生化性低钙血症(20.6%对33.9%;P = 0.028)和临床性低钙血症(12.7%对33%;P = 0.0003)的发生率。LM组所有有症状性低钙血症病例(16例中的16例)均被证明与甲状旁腺切除术有关,而未使用LM的患者中这一比例为76.9%(39例中的30例)(P = 0.046)。报告显示RLN损伤率有下降趋势,尽管在统计学上不显著,未使用LM时单侧短暂性、单侧永久性和双侧短暂性麻痹率分别为6.8%、2.5%和1.7%,使用LM时分别为4.8%、2.4%和0.8%(P分别为0.69、1和0.61)。我们的结果确实支持在全甲状腺切除术中常规使用LM。

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