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与结节性多动脉炎相关的肝动脉瘤自发性破裂。

Spontaneous rupture of hepatic artery aneurysm associated with polyarteritis nodosa.

作者信息

Parent Brodie A, Cho Sung W, Buck David G, Nalesnik Michael A, Gamblin T Clark

机构信息

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

出版信息

Am Surg. 2010 Dec;76(12):1416-9. doi: 10.1177/000313481007601230.

Abstract

Polyarteritis nodosa (PAN) is a vasculitis, which often involves small and medium sized visceral arteries. This condition may result in multifocal aneurismal formation and end-organ damage. Uncommonly, PAN may present with rupture of hepatic artery aneurysms. Here, we report a rare case of a ruptured intrahepatic aneurysm associated with PAN. A 79-year-old woman presenting with abdominal pain had CT scan of the abdomen, which revealed hematoma in the right hepatic lobe. Visceral angiogram confirmed pseudo-aneurysm of a right hepatic arterial branch, and this was managed with endovascular coil embolization. The diagnosis of PAN was made and corticosteroid therapy was initiated. We also performed a literature review to define this condition's demographics, clinical presentations, and appropriate management. The review revealed 17 published cases of ruptured PAN-related intrahepatic aneurysms. We conclude that unexplained findings of visceral arterial aneurysms should prompt investigations for vasculitis as the etiology.

摘要

结节性多动脉炎(PAN)是一种血管炎,常累及中小尺寸的内脏动脉。这种病症可能导致多灶性动脉瘤形成和终末器官损害。罕见的是,PAN可能表现为肝动脉瘤破裂。在此,我们报告一例与PAN相关的肝内动脉瘤破裂的罕见病例。一名79岁腹痛女性接受了腹部CT扫描,结果显示右肝叶有血肿。内脏血管造影证实右肝动脉分支存在假性动脉瘤,对此采用血管内弹簧圈栓塞治疗。确诊为PAN后开始使用皮质类固醇治疗。我们还进行了文献综述,以明确该病症的人口统计学特征、临床表现和适当的治疗方法。综述发现了17例已发表的PAN相关肝内动脉瘤破裂病例。我们得出结论,内脏动脉动脉瘤的不明原因发现应促使对血管炎病因进行调查。

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