Department of Neurology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA.
Int J Neurosci. 2011 May;121(5):267-70. doi: 10.3109/00207454.2010.550405. Epub 2011 Jan 26.
Spontaneous intracranial hemorrhage (S-ICH) often leads to significant morbidity and mortality. Clinical scoring systems can predict the mortality and functional outcome after ICH (FUNC score). FOUR score is a recently developed coma scale that incorporates brainstem reflexes. We propose that the combination of FUNC and FOUR scores will be a better prognostic indicator than either FUNC or FOUR score alone for S-ICH patients.
We conducted a retrospective chart review of all S-ICH patients (>18 years of age) from January 2008 to May 2010. ICH volume was calculated using the ABC/2 formula. FUNC (≤ 5 or >5) and FOUR (≤ 10 and >10) scores were calculated from admission data. Statistical analyses included chi-square test, positive predictive value, and relative risk assessment.
Total number of patients was 92. The mean age of presentation was 64.6 ± 15.6 years (range: 27-95 years). Male to female ratio was 1.6:1. Combined FUNC score ≤ 5 and FOUR score ≤ 10 (F2 score; 95%) had higher positive predictive value for mortality than either FUNC score ≤ 5 (82%) or FOUR score ≤ 10 (81%).
The combination of the FUNC and the FOUR scoring system is a better prognostication indicator for S-ICH patients than either FUNC or FOUR score.
自发性脑出血（S-ICH）常导致严重的发病率和死亡率。临床评分系统可预测 ICH 后的死亡率和功能结局（FUNC 评分）。FOUR 评分是一种新开发的包含脑干反射的昏迷评分。我们提出，FUNC 和 FOUR 评分的组合将是 S-ICH 患者比 FUNC 或 FOUR 评分更优的预后指标。
我们对 2008 年 1 月至 2010 年 5 月期间所有 S-ICH 患者（>18 岁）进行了回顾性图表审查。使用 ABC/2 公式计算 ICH 体积。FUNC（≤5 或>5）和 FOUR（≤10 和>10）评分根据入院数据计算。统计分析包括卡方检验、阳性预测值和相对风险评估。
总患者人数为 92 人。发病时的平均年龄为 64.6±15.6 岁（范围：27-95 岁）。男女比例为 1.6:1。FUNC 评分≤5 和 FOUR 评分≤10（F2 评分；95%）的死亡率阳性预测值高于 FUNC 评分≤5（82%）或 FOUR 评分≤10（81%）。
FUNC 和 FOUR 评分系统的组合是 S-ICH 患者比 FUNC 或 FOUR 评分更优的预后指标。
