Research Center, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.
Mol Biol Evol. 2011 Jul;28(7):1957-62. doi: 10.1093/molbev/msr024. Epub 2011 Jan 25.
Recent work on the Neandertal genome has raised the possibility of admixture between Neandertals and the expanding population of Homo sapiens who left Africa between 80 and 50 Kya (thousand years ago) to colonize the rest of the world. Here, we provide evidence of a notable presence (9% overall) of a Neandertal-derived X chromosome segment among all contemporary human populations outside Africa. Our analysis of 6,092 X-chromosomes from all inhabited continents supports earlier contentions that a mosaic of lineages of different time depths and different geographic provenance could have contributed to the genetic constitution of modern humans. It indicates a very early admixture between expanding African migrants and Neandertals prior to or very early on the route of the out-of-Africa expansion that led to the successful colonization of the planet.
最近对尼安德特人基因组的研究提出了这样一种可能性，即在 8 万至 5 万年前离开非洲、开拓世界其他地区的扩张中的智人种群与尼安德特人之间存在混合。在这里，我们提供了证据表明，在非洲以外的所有当代人类群体中，存在着显著的（总体为 9%）尼安德特人衍生的 X 染色体片段。我们对来自所有有人居住的大陆的 6092 条 X 染色体的分析支持了更早的观点，即不同时间深度和不同地理来源的谱系的马赛克可能促成了现代人的基因构成。这表明，在导致成功殖民地球的走出非洲扩张的路线上，扩张中的非洲移民与尼安德特人之间很早就发生了混合。
