Georgios Tsoulfas, Manousos Georgios Pramateftakis, Ioannis Kanellos, Department of Surgery, Aristoteleion University of Thessaloniki, Thessaloniki 54622, Greece.
World J Gastrointest Oncol. 2011 Jan 15;3(1):1-9. doi: 10.4251/wjgo.v3.i1.1.
Colorectal carcinoma is one of the most frequent cancers in Western societies with an incidence of around 700 per million people. About half of the patients develop metastases from the primary tumor and liver is the primary metastatic site. Improved survival rates after hepatectomy for metastatic colorectal cancer have been reported in the last few years and these may be the result of a variety of factors, such as advances in systemic chemotherapy, radiographic imaging techniques that permit more accurate determination of the extent and location of the metastatic burden, local ablation methods, and in surgical techniques of hepatic resection. These have led to a more aggressive approach towards liver metastatic disease, resulting in longer survival. The goal of this paper is to review the role of various forms of surgery in the treatment of hepatic metastases from colorectal cancer.
结直肠癌是西方社会最常见的癌症之一,发病率约为每百万分之 700。约一半的患者会从原发性肿瘤发展为转移瘤,而肝脏是原发性转移部位。近年来,转移性结直肠癌患者接受肝切除术后的生存率有所提高,这可能是多种因素的结果,如系统化疗的进步、能够更准确地确定转移瘤范围和位置的影像学技术、局部消融方法以及肝切除术的外科技术。这些导致了对肝转移疾病更积极的治疗方法,从而延长了患者的生存时间。本文的目的是回顾各种形式的手术在治疗结直肠癌肝转移中的作用。