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结直肠癌肝转移的外科治疗。

Surgical treatment of hepatic metastases from colorectal cancer.

机构信息

Georgios Tsoulfas, Manousos Georgios Pramateftakis, Ioannis Kanellos, Department of Surgery, Aristoteleion University of Thessaloniki, Thessaloniki 54622, Greece.

出版信息

World J Gastrointest Oncol. 2011 Jan 15;3(1):1-9. doi: 10.4251/wjgo.v3.i1.1.

DOI:10.4251/wjgo.v3.i1.1
PMID:21267397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3026051/
Abstract

Colorectal carcinoma is one of the most frequent cancers in Western societies with an incidence of around 700 per million people. About half of the patients develop metastases from the primary tumor and liver is the primary metastatic site. Improved survival rates after hepatectomy for metastatic colorectal cancer have been reported in the last few years and these may be the result of a variety of factors, such as advances in systemic chemotherapy, radiographic imaging techniques that permit more accurate determination of the extent and location of the metastatic burden, local ablation methods, and in surgical techniques of hepatic resection. These have led to a more aggressive approach towards liver metastatic disease, resulting in longer survival. The goal of this paper is to review the role of various forms of surgery in the treatment of hepatic metastases from colorectal cancer.

摘要

结直肠癌是西方社会最常见的癌症之一,发病率约为每百万分之 700。约一半的患者会从原发性肿瘤发展为转移瘤,而肝脏是原发性转移部位。近年来,转移性结直肠癌患者接受肝切除术后的生存率有所提高,这可能是多种因素的结果,如系统化疗的进步、能够更准确地确定转移瘤范围和位置的影像学技术、局部消融方法以及肝切除术的外科技术。这些导致了对肝转移疾病更积极的治疗方法,从而延长了患者的生存时间。本文的目的是回顾各种形式的手术在治疗结直肠癌肝转移中的作用。

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本文引用的文献

1
Outcomes of intensive surveillance after resection of hepatic colorectal metastases.肝结直肠转移瘤切除术后强化监测的结果。
Br J Surg. 2010 Oct;97(10):1552-60. doi: 10.1002/bjs.7136.
2
Surgical strategies for synchronous colorectal liver metastases in 156 consecutive patients: classic, combined or reverse strategy?156 例结直肠肝转移同期患者的手术策略:经典、联合还是反转策略?
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Liver transplantation for colorectal liver metastases: revisiting the concept.肝移植治疗结直肠癌肝转移:重新审视这一概念。
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Short- and medium-term results of totally laparoscopic resection for colorectal liver metastases.腹腔镜结直肠肝转移瘤完全切除术的近期和中期结果。
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5
Conditional survival after surgical resection of colorectal liver metastasis: an international multi-institutional analysis of 949 patients.结直肠肝转移术后的条件生存:949 例国际多机构分析。
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6
Survival after hepatic resection for metastatic colorectal cancer: trends in outcomes for 1,600 patients during two decades at a single institution.肝切除治疗转移性结直肠癌的生存情况:单中心 20 年 1600 例患者结局的变化趋势。
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Predictors of a true complete response among disappearing liver metastases from colorectal cancer after chemotherapy.化疗后结直肠癌肝转移消失后真正完全缓解的预测因素。
Cancer. 2010 Mar 15;116(6):1502-9. doi: 10.1002/cncr.24912.
8
Impact of portal vein embolization on long-term survival of patients with primarily unresectable colorectal liver metastases.门静脉栓塞对不可切除的结直肠癌肝转移患者长期生存的影响。
Br J Surg. 2010 Feb;97(2):240-50. doi: 10.1002/bjs.6756.
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Evolution in surgery: influence of minimally invasive approaches on the hepatobiliary surgeon.手术的演变:微创方法对肝胆外科医生的影响。
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Activation of host wound responses in breast cancer microenvironment.激活乳腺癌微环境中的宿主创伤反应。
Clin Cancer Res. 2009 Nov 15;15(22):7020-8. doi: 10.1158/1078-0432.CCR-09-1126. Epub 2009 Nov 3.