Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.
Hepatobiliary Pancreat Dis Int. 2011 Feb;10(1):26-9. doi: 10.1016/s1499-3872(11)60003-9.
There is a constant and global shortage of deceased-donor organs for transplantation. Ways to identify areas for securing potential deceased-donor organs may improve the supply and hence benefit more patients in need of transplantation.
We looked into the disparity of the number of deceased-donor liver transplantation (DDLT) performed at our hospital on different days of the weeks from January 2000 to the end of December 2009 (237 DDLTs). The number of DDLT performed on each day was compared with the other days of the week.
It was apparent that there were fewer DDLTs on Mondays, as shown by the numbers of DDLT performed on different days of the week in an ascending order: Monday 18 (7.6%), Sunday 30 (12.7%), Thursday 34 (14.3%), Friday 36 (15.2%), Wednesday 38 (16.0%), Tuesday 40 (16.9%), and Saturday 41 (17.3%). The difference reached statistical significance when Monday was compared with Tuesday (P=0.019), Wednesday (P=0.010), Friday (P=0.021), and Saturday (P=0.007). It was twice as unlikely a DDLT would be performed on Monday as compared with other days. Such a trend did not change even with an increase in the number of deceased-donor liver grafts in the last year. As consent to donation was obtained from the donor family the day before DDLT, fewer consents were thus obtained on Sundays.
These findings suggested that deceased-donor organ donation activities were less active on Sundays and could be improved. This further raises the concern of possible wastage of potential cases of organ donation.
全球范围内一直存在可供移植的已故供体器官短缺的问题。寻找潜在已故供体器官的方法可能会增加器官供应,从而使更多需要移植的患者受益。
我们研究了 2000 年 1 月至 2009 年 12 月期间我院不同日期进行的 237 例肝移植(DDLT)数量差异。将每天进行的 DDLT 数量与一周中的其他几天进行比较。
结果表明,周一进行的 DDLT 较少,一周中不同日期的 DDLT 数量呈递增顺序:周一 18 例(7.6%)、周日 30 例(12.7%)、周四 34 例(14.3%)、周五 36 例(15.2%)、周三 38 例(16.0%)、周二 40 例(16.9%)和周六 41 例(17.3%)。周一与周二(P=0.019)、周三(P=0.010)、周五(P=0.021)和周六(P=0.007)相比,差异具有统计学意义。周一进行 DDLT 的可能性是其他日期的一半。即使去年供体肝移植数量增加,这种趋势也没有改变。由于 DDLT 前一天从供体家属那里获得同意,因此周日获得的同意较少。
这些发现表明,周日已故供体器官捐献活动不太活跃,可以加以改善。这进一步引起了对潜在器官捐献案例浪费的关注。